A European Respiratory Society technical standard: exhaled biomarkers in lung disease
Breath tests cover the fraction of nitric oxide in expired gas ( ), volatile organic compounds (VOCs), variables in exhaled breath condensate (EBC) and other measurements. For EBC and for , official recommendations for standardised procedures are more than 10 years old and there is none for exhaled...
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| Veröffentlicht in: | The European respiratory journal 2017-04, Vol.49 (4), p.1600965-1600965 |
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| creator | Horváth, Ildiko Barnes, Peter J Loukides, Stelios Sterk, Peter J Högman, Marieann Olin, Anna-Carin Amann, Anton Antus, Balazs Baraldi, Eugenio Bikov, Andras Boots, Agnes W Bos, Lieuwe D Brinkman, Paul Bucca, Caterina Carpagnano, Giovanna E Corradi, Massimo Cristescu, Simona de Jongste, Johan C Dinh-Xuan, Anh-Tuan Dompeling, Edward Fens, Niki Fowler, Stephen Hohlfeld, Jens M Holz, Olaf Jöbsis, Quirijn Van De Kant, Kim Knobel, Hugo H Kostikas, Konstantinos Lehtimäki, Lauri Lundberg, Jon Montuschi, Paolo Van Muylem, Alain Pennazza, Giorgio Reinhold, Petra Ricciardolo, Fabio L M Rosias, Philippe Santonico, Marco van der Schee, Marc P van Schooten, Frederik-Jan Spanevello, Antonio Tonia, Thomy Vink, Teunis J |
| description | Breath tests cover the fraction of nitric oxide in expired gas (
), volatile organic compounds (VOCs), variables in exhaled breath condensate (EBC) and other measurements. For EBC and for
, official recommendations for standardised procedures are more than 10 years old and there is none for exhaled VOCs and particles. The aim of this document is to provide technical standards and recommendations for sample collection and analytic approaches and to highlight future research priorities in the field. For EBC and
, new developments and advances in technology have been evaluated in the current document. This report is not intended to provide clinical guidance on disease diagnosis and management.Clinicians and researchers with expertise in exhaled biomarkers were invited to participate. Published studies regarding methodology of breath tests were selected, discussed and evaluated in a consensus-based manner by the Task Force members.Recommendations for standardisation of sampling, analysing and reporting of data and suggestions for research to cover gaps in the evidence have been created and summarised.Application of breath biomarker measurement in a standardised manner will provide comparable results, thereby facilitating the potential use of these biomarkers in clinical practice. |
| doi_str_mv | 10.1183/13993003.00965-2016 |
| format | Article |
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), volatile organic compounds (VOCs), variables in exhaled breath condensate (EBC) and other measurements. For EBC and for
, official recommendations for standardised procedures are more than 10 years old and there is none for exhaled VOCs and particles. The aim of this document is to provide technical standards and recommendations for sample collection and analytic approaches and to highlight future research priorities in the field. For EBC and
, new developments and advances in technology have been evaluated in the current document. This report is not intended to provide clinical guidance on disease diagnosis and management.Clinicians and researchers with expertise in exhaled biomarkers were invited to participate. Published studies regarding methodology of breath tests were selected, discussed and evaluated in a consensus-based manner by the Task Force members.Recommendations for standardisation of sampling, analysing and reporting of data and suggestions for research to cover gaps in the evidence have been created and summarised.Application of breath biomarker measurement in a standardised manner will provide comparable results, thereby facilitating the potential use of these biomarkers in clinical practice.</description><identifier>ISSN: 0903-1936</identifier><identifier>ISSN: 1399-3003</identifier><identifier>EISSN: 1399-3003</identifier><identifier>DOI: 10.1183/13993003.00965-2016</identifier><identifier>PMID: 28446552</identifier><language>eng</language><publisher>England: European Respiratory Society Journals Ltd</publisher><subject>analysis ; Arbetsmedicin och miljömedicin ; Biomarkers ; Biomarkers - analysis ; breath condensate ph ; Breath tests ; Breath Tests - methods ; Data processing ; electronic nose ; Europe ; Exhalation ; extended no ; Humans ; Lung diseases ; Lung Diseases - diagnosis ; Lung Diseases - therapy ; Lungmedicin och allergi ; magnetic-resonance-spectroscopy ; mass-spectrometric analysis ; nasal nitric-oxide ; Nitric oxide ; Nitric Oxide - analysis ; obstructive pulmonary-disease ; Occupational Health and Environmental Health ; Organic compounds ; primary ciliary dyskinesia ; Respiratory Medicine and Allergy ; Respiratory System ; sleep-apnea syndrome ; Societies, Medical ; VOCs ; Volatile organic compounds ; Volatile Organic Compounds - analysis</subject><ispartof>The European respiratory journal, 2017-04, Vol.49 (4), p.1600965-1600965</ispartof><rights>Copyright ©ERS 2017.</rights><rights>Copyright European Respiratory Society Journals Ltd. Apr 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c590t-bf47f7a2783bb608b258145328ea1628859f660469aa10a470527197842133b43</citedby><cites>FETCH-LOGICAL-c590t-bf47f7a2783bb608b258145328ea1628859f660469aa10a470527197842133b43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,550,776,780,881,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28446552$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-322843$$DView record from Swedish Publication Index$$Hfree_for_read</backlink><backlink>$$Uhttps://gup.ub.gu.se/publication/253767$$DView record from Swedish Publication Index$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:135711093$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Horváth, Ildiko</creatorcontrib><creatorcontrib>Barnes, Peter J</creatorcontrib><creatorcontrib>Loukides, Stelios</creatorcontrib><creatorcontrib>Sterk, Peter J</creatorcontrib><creatorcontrib>Högman, Marieann</creatorcontrib><creatorcontrib>Olin, Anna-Carin</creatorcontrib><creatorcontrib>Amann, Anton</creatorcontrib><creatorcontrib>Antus, Balazs</creatorcontrib><creatorcontrib>Baraldi, Eugenio</creatorcontrib><creatorcontrib>Bikov, Andras</creatorcontrib><creatorcontrib>Boots, Agnes W</creatorcontrib><creatorcontrib>Bos, Lieuwe D</creatorcontrib><creatorcontrib>Brinkman, Paul</creatorcontrib><creatorcontrib>Bucca, Caterina</creatorcontrib><creatorcontrib>Carpagnano, Giovanna E</creatorcontrib><creatorcontrib>Corradi, Massimo</creatorcontrib><creatorcontrib>Cristescu, Simona</creatorcontrib><creatorcontrib>de Jongste, Johan C</creatorcontrib><creatorcontrib>Dinh-Xuan, Anh-Tuan</creatorcontrib><creatorcontrib>Dompeling, Edward</creatorcontrib><creatorcontrib>Fens, Niki</creatorcontrib><creatorcontrib>Fowler, Stephen</creatorcontrib><creatorcontrib>Hohlfeld, Jens M</creatorcontrib><creatorcontrib>Holz, Olaf</creatorcontrib><creatorcontrib>Jöbsis, Quirijn</creatorcontrib><creatorcontrib>Van De Kant, Kim</creatorcontrib><creatorcontrib>Knobel, Hugo H</creatorcontrib><creatorcontrib>Kostikas, Konstantinos</creatorcontrib><creatorcontrib>Lehtimäki, Lauri</creatorcontrib><creatorcontrib>Lundberg, Jon</creatorcontrib><creatorcontrib>Montuschi, Paolo</creatorcontrib><creatorcontrib>Van Muylem, Alain</creatorcontrib><creatorcontrib>Pennazza, Giorgio</creatorcontrib><creatorcontrib>Reinhold, Petra</creatorcontrib><creatorcontrib>Ricciardolo, Fabio L M</creatorcontrib><creatorcontrib>Rosias, Philippe</creatorcontrib><creatorcontrib>Santonico, Marco</creatorcontrib><creatorcontrib>van der Schee, Marc P</creatorcontrib><creatorcontrib>van Schooten, Frederik-Jan</creatorcontrib><creatorcontrib>Spanevello, Antonio</creatorcontrib><creatorcontrib>Tonia, Thomy</creatorcontrib><creatorcontrib>Vink, Teunis J</creatorcontrib><title>A European Respiratory Society technical standard: exhaled biomarkers in lung disease</title><title>The European respiratory journal</title><addtitle>Eur Respir J</addtitle><description>Breath tests cover the fraction of nitric oxide in expired gas (
), volatile organic compounds (VOCs), variables in exhaled breath condensate (EBC) and other measurements. For EBC and for
, official recommendations for standardised procedures are more than 10 years old and there is none for exhaled VOCs and particles. The aim of this document is to provide technical standards and recommendations for sample collection and analytic approaches and to highlight future research priorities in the field. For EBC and
, new developments and advances in technology have been evaluated in the current document. This report is not intended to provide clinical guidance on disease diagnosis and management.Clinicians and researchers with expertise in exhaled biomarkers were invited to participate. Published studies regarding methodology of breath tests were selected, discussed and evaluated in a consensus-based manner by the Task Force members.Recommendations for standardisation of sampling, analysing and reporting of data and suggestions for research to cover gaps in the evidence have been created and summarised.Application of breath biomarker measurement in a standardised manner will provide comparable results, thereby facilitating the potential use of these biomarkers in clinical practice.</description><subject>analysis</subject><subject>Arbetsmedicin och miljömedicin</subject><subject>Biomarkers</subject><subject>Biomarkers - analysis</subject><subject>breath condensate ph</subject><subject>Breath tests</subject><subject>Breath Tests - methods</subject><subject>Data processing</subject><subject>electronic nose</subject><subject>Europe</subject><subject>Exhalation</subject><subject>extended no</subject><subject>Humans</subject><subject>Lung diseases</subject><subject>Lung Diseases - diagnosis</subject><subject>Lung Diseases - therapy</subject><subject>Lungmedicin och allergi</subject><subject>magnetic-resonance-spectroscopy</subject><subject>mass-spectrometric analysis</subject><subject>nasal nitric-oxide</subject><subject>Nitric oxide</subject><subject>Nitric Oxide - analysis</subject><subject>obstructive pulmonary-disease</subject><subject>Occupational Health and Environmental Health</subject><subject>Organic compounds</subject><subject>primary ciliary dyskinesia</subject><subject>Respiratory Medicine and Allergy</subject><subject>Respiratory System</subject><subject>sleep-apnea syndrome</subject><subject>Societies, Medical</subject><subject>VOCs</subject><subject>Volatile organic compounds</subject><subject>Volatile Organic Compounds - analysis</subject><issn>0903-1936</issn><issn>1399-3003</issn><issn>1399-3003</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>D8T</sourceid><recordid>eNqFkl1rFDEUhoModlv9BYIMeONFpyY5-fRuqfUDCoJab0NmJrNNOzuZJhN0_70Zd9sLQb1KeHnOy-HwIPSC4DNCFLwhoDVgDGcYa8Friol4hFZLWi_xY7TCGkNNNIgjdJzSDS4EA_IUHVHFmOCcrtDVurrIMUzOjtUXlyYf7RzirvoaWu_mXTW79nr0rR2qNNuxs7F7W7mf13ZwXdX4sLXx1sVU-bEa8ripOp-cTe4ZetLbIbnnh_cEXb2_-Hb-sb78_OHT-fqybrnGc930TPbSUqmgaQRWDeWKMA5UOUsEVYrrXgjMhLaWYMsk5lQSLRWjBKBhcILqfW_64abcmCn6stHOBOvNIbotP2eYlpTif_KbPJkSbfLCUw5SyMKf_pV_57-vTYgbk7MBWi4KBX-9x6cY7rJLs9n61LphsKMLORmiMZGMACf_R5WmkoIQtKCv_kBvQo5juWspVKCpllwVCvZUG0NK0fUPyxJsFl_MvS_mty9m8aVMvTx052bruoeZe0HgF6yGuMY</recordid><startdate>20170401</startdate><enddate>20170401</enddate><creator>Horváth, Ildiko</creator><creator>Barnes, Peter J</creator><creator>Loukides, Stelios</creator><creator>Sterk, Peter J</creator><creator>Högman, Marieann</creator><creator>Olin, Anna-Carin</creator><creator>Amann, Anton</creator><creator>Antus, Balazs</creator><creator>Baraldi, Eugenio</creator><creator>Bikov, Andras</creator><creator>Boots, Agnes W</creator><creator>Bos, Lieuwe D</creator><creator>Brinkman, Paul</creator><creator>Bucca, Caterina</creator><creator>Carpagnano, Giovanna E</creator><creator>Corradi, Massimo</creator><creator>Cristescu, Simona</creator><creator>de Jongste, Johan C</creator><creator>Dinh-Xuan, Anh-Tuan</creator><creator>Dompeling, Edward</creator><creator>Fens, Niki</creator><creator>Fowler, Stephen</creator><creator>Hohlfeld, Jens M</creator><creator>Holz, Olaf</creator><creator>Jöbsis, Quirijn</creator><creator>Van De Kant, Kim</creator><creator>Knobel, Hugo H</creator><creator>Kostikas, Konstantinos</creator><creator>Lehtimäki, Lauri</creator><creator>Lundberg, Jon</creator><creator>Montuschi, Paolo</creator><creator>Van Muylem, Alain</creator><creator>Pennazza, Giorgio</creator><creator>Reinhold, Petra</creator><creator>Ricciardolo, Fabio L M</creator><creator>Rosias, Philippe</creator><creator>Santonico, Marco</creator><creator>van der Schee, Marc P</creator><creator>van Schooten, Frederik-Jan</creator><creator>Spanevello, Antonio</creator><creator>Tonia, Thomy</creator><creator>Vink, Teunis J</creator><general>European Respiratory Society Journals Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope><scope>ADTPV</scope><scope>AOWAS</scope><scope>DF2</scope><scope>F1U</scope><scope>D8T</scope><scope>ZZAVC</scope></search><sort><creationdate>20170401</creationdate><title>A European Respiratory Society technical standard: exhaled biomarkers in lung disease</title><author>Horváth, Ildiko ; Barnes, Peter J ; Loukides, Stelios ; Sterk, Peter J ; Högman, Marieann ; Olin, Anna-Carin ; Amann, Anton ; Antus, Balazs ; Baraldi, Eugenio ; Bikov, Andras ; Boots, Agnes W ; Bos, Lieuwe D ; Brinkman, Paul ; Bucca, Caterina ; Carpagnano, Giovanna E ; Corradi, Massimo ; Cristescu, Simona ; de Jongste, Johan C ; Dinh-Xuan, Anh-Tuan ; Dompeling, Edward ; Fens, Niki ; Fowler, Stephen ; Hohlfeld, Jens M ; Holz, Olaf ; Jöbsis, Quirijn ; Van De Kant, Kim ; Knobel, Hugo H ; Kostikas, Konstantinos ; Lehtimäki, Lauri ; Lundberg, Jon ; Montuschi, Paolo ; Van Muylem, Alain ; Pennazza, Giorgio ; Reinhold, Petra ; Ricciardolo, Fabio L M ; Rosias, Philippe ; Santonico, Marco ; van der Schee, Marc P ; van Schooten, Frederik-Jan ; Spanevello, Antonio ; Tonia, Thomy ; Vink, Teunis J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c590t-bf47f7a2783bb608b258145328ea1628859f660469aa10a470527197842133b43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>analysis</topic><topic>Arbetsmedicin och miljömedicin</topic><topic>Biomarkers</topic><topic>Biomarkers - 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), volatile organic compounds (VOCs), variables in exhaled breath condensate (EBC) and other measurements. For EBC and for
, official recommendations for standardised procedures are more than 10 years old and there is none for exhaled VOCs and particles. The aim of this document is to provide technical standards and recommendations for sample collection and analytic approaches and to highlight future research priorities in the field. For EBC and
, new developments and advances in technology have been evaluated in the current document. This report is not intended to provide clinical guidance on disease diagnosis and management.Clinicians and researchers with expertise in exhaled biomarkers were invited to participate. Published studies regarding methodology of breath tests were selected, discussed and evaluated in a consensus-based manner by the Task Force members.Recommendations for standardisation of sampling, analysing and reporting of data and suggestions for research to cover gaps in the evidence have been created and summarised.Application of breath biomarker measurement in a standardised manner will provide comparable results, thereby facilitating the potential use of these biomarkers in clinical practice.</abstract><cop>England</cop><pub>European Respiratory Society Journals Ltd</pub><pmid>28446552</pmid><doi>10.1183/13993003.00965-2016</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0903-1936 |
| ispartof | The European respiratory journal, 2017-04, Vol.49 (4), p.1600965-1600965 |
| issn | 0903-1936 1399-3003 1399-3003 |
| language | eng |
| recordid | cdi_swepub_primary_oai_swepub_ki_se_497220 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; SWEPUB Freely available online |
| subjects | analysis Arbetsmedicin och miljömedicin Biomarkers Biomarkers - analysis breath condensate ph Breath tests Breath Tests - methods Data processing electronic nose Europe Exhalation extended no Humans Lung diseases Lung Diseases - diagnosis Lung Diseases - therapy Lungmedicin och allergi magnetic-resonance-spectroscopy mass-spectrometric analysis nasal nitric-oxide Nitric oxide Nitric Oxide - analysis obstructive pulmonary-disease Occupational Health and Environmental Health Organic compounds primary ciliary dyskinesia Respiratory Medicine and Allergy Respiratory System sleep-apnea syndrome Societies, Medical VOCs Volatile organic compounds Volatile Organic Compounds - analysis |
| title | A European Respiratory Society technical standard: exhaled biomarkers in lung disease |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-21T20%3A38%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_swepu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20European%20Respiratory%20Society%20technical%20standard:%20exhaled%20biomarkers%20in%20lung%20disease&rft.jtitle=The%20European%20respiratory%20journal&rft.au=Horv%C3%A1th,%20Ildiko&rft.date=2017-04-01&rft.volume=49&rft.issue=4&rft.spage=1600965&rft.epage=1600965&rft.pages=1600965-1600965&rft.issn=0903-1936&rft.eissn=1399-3003&rft_id=info:doi/10.1183/13993003.00965-2016&rft_dat=%3Cproquest_swepu%3E1901741351%3C/proquest_swepu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1983929758&rft_id=info:pmid/28446552&rfr_iscdi=true |