Adhesion profile and differentiation capacity of human adipose tissue derived mesenchymal stem cells grown on metal ion (Zn, Ag and Cu) doped hydroxyapatite nano-coated surfaces

[Display omitted] •Novelty, hMSCs were grown on fabricated metal ion (Zn, Ag and Cu) doped HAP nano-coating surfaces.•Nano-powders are biocompatible and have no negative effects on the hMSCs proliferation.•Promoted osteogenic differentiation by surfaces without exogenous osteogenic stimulation.•Enha...

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Veröffentlicht in:	Colloids and surfaces, B, Biointerfaces B, Biointerfaces, 2017-07, Vol.155, p.415-428
Hauptverfasser:	Bostancioglu, R. Beklem, Gurbuz, Mevlut, Akyurekli, Ayse Gul, Dogan, Aydin, Koparal, A. Savas, Koparal, A. Tansu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesion Adipose Tissue - cytology Biocompability Biomaterial Cell Adhesion - drug effects Cell Adhesion - genetics Cell Differentiation - drug effects Cell Differentiation - genetics Cell Survival - drug effects Cell Survival - genetics Cells, Cultured Coated Materials, Biocompatible - chemistry Coated Materials, Biocompatible - pharmacology Copper - chemistry Durapatite - chemistry Durapatite - pharmacology Gene expression Gene Expression Profiling - methods hMSCs Humans Hydroxyapatite Mesenchymal Stromal Cells - drug effects Mesenchymal Stromal Cells - metabolism Metal ion Microscopy, Electron, Scanning Nanomaterial Nanostructures - chemistry Nanostructures - ultrastructure Osteogenesis - drug effects Osteogenesis - genetics Osteogenic differentiation Silver - chemistry Surface Properties Zinc - chemistry
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