A novel mouse model of radiation-induced cancer survivorship diseases of the gut

A deeper understanding of the radiation-induced pathophysiological processes that develop in the gut is imperative to prevent, alleviate, or eliminate cancer survivorship diseases after radiotherapy to the pelvic area. Most rodent models of high-dose gastrointestinal radiation injury are limited by...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2017-11, Vol.313 (5), p.G456-G466
Hauptverfasser:	Bull, Cecilia, Malipatlolla, Dilip, Kalm, Marie, Sjöberg, Fei, Alevronta, Eleftheria, Grandér, Rita, Sultanian, Pedram, Persson, Linda, Boström, Martina, Eriksson, Yohanna, Swanpalmer, John, Wold, Agnes E, Blomgren, Klas, Björk-Eriksson, Thomas, Steineck, Gunnar
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Animal models Animals Apoptosis Cancer Cancer and Oncology Cancer och onkologi Cell death Cell Survival Colorectal Neoplasms - etiology Colorectal Neoplasms - pathology Degeneration Digestive system Disease Models, Animal Dose Fractionation Fibrosis Gastrointestinal diseases Gastrointestinal tract Gastrointestinal Tract - injuries Gastrointestinal Tract - pathology Gastrointestinal Tract - radiation effects Hypoxia Macrophages Medicin och hälsovetenskap Mice Neoplasms, Radiation-Induced - pathology Pelvis Pelvis - radiation effects Radiation Radiation Injuries, Experimental - pathology Radiation therapy Radiotherapy - adverse effects Radiotherapy - methods Survival
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