In vitro genotoxicity of airborne Ni‐NP in air–liquid interface

Studies using advanced toxicological methods enabling in vitro conditions that are more realistic are currently needed for understanding the risks of pulmonary exposure to airborne nanoparticles. Owing to the carcinogenicity of certain nickel compounds, the increased production of nickel nanoparticl...

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Veröffentlicht in:	Journal of applied toxicology 2017-12, Vol.37 (12), p.1420-1427
Hauptverfasser:	Latvala, Siiri, Vare, Daniel, Karlsson, Hanna L., Elihn, Karine
Format:	Artikel
Sprache:	eng
Schlagworte:	Air Pollutants - toxicity air-liquid interface alkaline DNA unwinding Animals Base excision repair Carcinogenicity Carcinogens Cell Culture Techniques Cell Line Cell Survival - drug effects Cricetulus Cytotoxicity Damage Deoxyribonucleic acid DNA DNA Damage DNA repair Exposure Fibroblasts Genotoxicity HPRT Hypoxanthine Phosphoribosyltransferase - genetics In vitro methods and tests Inhibitors Lesions Lungs Medicin och hälsovetenskap Metal Nanoparticles - toxicity Mutagenicity Mutagenicity Tests Mutagens - toxicity Mutation Nanoparticles nanotoxicology Nickel Nickel - toxicity Nickel compounds Occupational safety Particle Size Particulate Matter - toxicity Poly(ADP-ribose) polymerase Poly(ADP-ribose) Polymerase 1 Repair Toxicity Unwinding
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