Exosomal biomarkers in Down syndrome and Alzheimer's disease

Every person with Down syndrome (DS) has the characteristic features of Alzheimer's disease (AD) neuropathology in their brain by the age of forty, and most go on to develop AD dementia. Since people with DS show highly variable levels of baseline function, it is often difficult to identify ear...

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Veröffentlicht in:	FREE RADICAL BIOLOGY AND MEDICINE 2018-01, Vol.114, p.110-121
Hauptverfasser:	Hamlett, Eric D., Ledreux, Aurélie, Potter, Huntington, Chial, Heidi J., Patterson, David, Espinosa, Joaquin M., Bettcher, Brianne M., Granholm, Ann-Charlotte
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - diagnosis Alzheimer Disease - metabolism Alzheimer's disease Biomarkers - metabolism Down syndrome Down Syndrome - diagnosis Down Syndrome - metabolism Exosomes Exosomes - metabolism Humans Neurodegeneration Neuroinflammation Oxidative stress
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