Augmented Th17 differentiation in Trim21 deficiency promotes a stable phenotype of atherosclerotic plaques with high collagen content

Abstract Aims Patients with hyperlipidemia are at risk of atherosclerosis, but not all develop cardiovascular disease, highlighting the importance of other risk factors such as inflammation. Both the innate and adaptive arms of the immune system have been suggested in the initiation and propagation...

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Veröffentlicht in:Cardiovascular research 2018-01, Vol.114 (1), p.158-167
Hauptverfasser: Brauner, Susanna, Jiang, Xintong, Thorlacius, Gudny Ella, Lundberg, Anna M, Östberg, Therese, Yan, Zhong-Qun, Kuchroo, Vijay K, Hansson, Göran K, Wahren-Herlenius, Marie
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