Increased NK Cell Function After Cessation of Long-Term Nucleos(t)ide Analogue Treatment in Chronic Hepatitis B Is Associated With Liver Damage and HBsAg Loss

Structured discontinuation of nucleos(t)ide analogue treatment in chronic hepatitis B (CHB) augmented natural killer cell functionality. This was associated with alanine aminotransferase flares and functional cure of CHB at follow-up, suggesting a role for NK cells in clearance of HBV. Abstract Back...

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Veröffentlicht in:The Journal of infectious diseases 2018-04, Vol.217 (10), p.1656-1666
Hauptverfasser: Zimmer, Christine L, Rinker, Franziska, Höner zu Siederdissen, Christoph, Manns, Michael P, Wedemeyer, Heiner, Cornberg, Markus, Björkström, Niklas K
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Sprache:eng
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