Association of NOX2 subunits genetic variants with autoimmune diseases

A single nucleotide polymorphism in Ncf1 has been found with a major effect on chronic inflammatory autoimmune diseases in the rat with the surprising observation that a lower reactive oxygen response led to more severe diseases. This finding was subsequently reproduced in the mouse and the effect o...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Free radical biology & medicine 2018-09, Vol.125, p.72-80
Hauptverfasser:	Zhong, Jianghong, Olsson, Lina M., Urbonaviciute, Vilma, Yang, Min, Bäckdahl, Liselotte, Holmdahl, Rikard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoimmune diseases Autoimmune Diseases - genetics Autoimmune Diseases - pathology Humans NADPH Oxidase 2 - genetics Ncf1 NOX2 Polymorphism Polymorphism, Single Nucleotide ROS Signal Transduction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!