Dynamic lateral organization of opioid receptors (kappa, muwt and muN40D) in the plasma membrane at the nanoscale level

Using quantitative methods with single‐molecule sensitivity, fluorescence correlation spectroscopy and photoactivated localization microscopy, we characterized the nanoscale lateral dynamics and spatial organization of opioid receptors: kappa, mu, and mu isoform N40D. Experimental results supported...

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Veröffentlicht in:	Traffic (Copenhagen, Denmark) Denmark), 2018-09, Vol.19 (9), p.690-709
Hauptverfasser:	Rogacki, Maciej K., Golfetto, Ottavia, Tobin, Steven J., Li, Tianyi, Biswas, Sunetra, Jorand, Raphael, Zhang, Huiying, Radoi, Vlad, Ming, Yu, Svenningsson, Per, Ganjali, Daniel, Wakefield, Devin L., Sideris, Athanasios, Small, Alexander R., Terenius, Lars, Jovanović‐Talisman, Tijana, Vukojević, Vladana
Format:	Artikel
Sprache:	eng
Schlagworte:	Cholesterol Drug addiction dynamic lateral organization fluorescence correlation spectroscopy Fluorescence spectroscopy Ganglioside GM1 GPCR Localization nanoscopy Narcotics opioid receptor Opioid receptors (type kappa) Opioid receptors (type mu) Original Pain pair‐correlation photoactivated localization microscopy Population density Receptor density super‐resolution
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