Long-term outcomes of clinical complete responders after neoadjuvant treatment for rectal cancer in the International Watch & Wait Database (IWWD): an international multicentre registry study

The strategy of watch and wait (W&W) in patients with rectal cancer who achieve a complete clinical response (cCR) after neoadjuvant therapy is new and offers an opportunity for patients to avoid major resection surgery. However, evidence is based on small-to-moderate sized series from specialis...

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Veröffentlicht in:	LANCET 2018-06, Vol.391 (10139), p.2537-2545
Hauptverfasser:	van der Valk, Maxime J M, Hilling, Denise E, Bastiaannet, Esther, Meershoek-Klein Kranenbarg, Elma, Beets, Geerard L, Figueiredo, Nuno L, Habr-Gama, Angelita, Perez, Rodrigo O, Renehan, Andrew G, van de Velde, Cornelis J H, Ahlberg, Madeleine, Appelt, Ane, Asoglu, Oktar, Bär, Maria-Theresa, Barroca, Rita, Beets-Tan, Regina G H, Belgers, Eric H J, Bosker, Robbert J I, Breukink, Stéphanie O, Bujko, Krysztof, Carvalho, Carlos, Cunningham, Christopher, Creavin, Ben, D'Hoore, André, Gérard, Jean-Pierre, Gollins, Simon, Hoff, Christiaan, Holman, Fabian A, Hupkens, Britt J P, Iseas, Soledad, Jakobsen, Anders, Keshvari, Amir, Koopal, Sietze A, Kusters, Miranda, Langheinrich, Melanie, Leijtens, Jeroen W A, Maas, Monique, Malcomson, Lee, Mamedli, Zamam Z, Martling, Anna, Matzel, Klaus E, Melenhorst, Jarno, Morici, María L, Murad-Regadas, Sthela M, O'Dwyer, Sarah T, Peeters, Koen C M J, Rosa, Isadora, Rossi, Gustavo, Rutten, Harm J T, Sanchez Loria, Fernando, van der Sande, Marit E, São Julião, Guilherme P, Saunders, Mark, Sun Myint, Arthur, van der Sluis, Hedwig, Schiappa, Renaud, Scott, Nigel, Stoot, Jan H M B, Talsma, A Koen, Terrasson, Isabelle, Tokmak, Handan, Vaccaro, Carlos A, Vahrmeijer, Alexander L, Wasowicz, Daria K, Westreenen, Henderik L, Winter, Des C, Wolthuis, Albert M, Zimmerman, David D E
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Cancer Cancer therapies Chemotherapy Chemotherapy, Adjuvant - statistics & numerical data Colorectal cancer Comorbidity Disease-Free Survival Encryption Female Humans Incidence Intestine Male Metastases Middle Aged Neoplasm Recurrence, Local - epidemiology Ostomy Outcome Assessment (Health Care) - methods Patients Radiation therapy Rectal Neoplasms - drug therapy Rectal Neoplasms - pathology Rectal Neoplasms - radiotherapy Rectum Registries Regrowth Surgery Survival Therapy Tumors Watchful Waiting - statistics & numerical data
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