Early depletion of contact system in patients with sepsis: a prospective matched control observational study

Activation of the contact system generates bradykinin from high‐molecular‐weight kininogen and has been suggested to participate in the pathophysiology of sepsis. To test this, we prospectively measured bradykinin and high‐molecular‐weight kininogen levels in a cohort of sepsis patients requiring in...

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Veröffentlicht in:	APMIS : acta pathologica, microbiologica et immunologica Scandinavica microbiologica et immunologica Scandinavica, 2018-12, Vol.126 (12), p.892-898
Hauptverfasser:	Berkestedt, Ingrid, Andersson, Pia, Herwald, Heiko, Valik, John Karlsson, Sörensen, Ola, Bodelsson, Mikael
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Bradykinin Clinical Medicine contact system Densitometers Densitometry Depletion Electrical impedance high-molecular-weight Infectious Medicine Infektionsmedicin Intensive care kininogen Kininogens Klinisk medicin Medical and Health Sciences Medicin och hälsovetenskap Molecular weight Mortality Neurosurgery Observational studies Patients Sepsis Septic shock Substrates
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