Predicting clinical outcome and length of sick leave after surgery for lumbar spinal stenosis in Sweden: a multi-register evaluation
Purpose Lumbar spinal stenosis (LSS) can be surgically treated, with variable outcome. Studies have linked socioeconomic factors to outcome, but no nation-wide studies have been performed. This register-based study, including all patients surgically treated for LSS during 2008–2012 in Sweden, aimed...
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Veröffentlicht in: | European spine journal 2019-06, Vol.28 (6), p.1423-1432 |
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creator | Iderberg, Hanna Willers, Carl Borgström, Fredrik Hedlund, Rune Hägg, Olle Möller, Hans Ornstein, Ewald Sandén, Bengt Stalberg, Holger Torevall-Larsson, Hans Tullberg, Tycho Fritzell, Peter |
description | Purpose
Lumbar spinal stenosis (LSS) can be surgically treated, with variable outcome. Studies have linked socioeconomic factors to outcome, but no nation-wide studies have been performed. This register-based study, including all patients surgically treated for LSS during 2008–2012 in Sweden, aimed to determine predictive factors for the outcome of surgery.
Methods
Clinical and socioeconomic factors with impact on outcome in LSS surgery were identified in several high-coverage registers, e.g., the national quality registry for spine surgery (Swespine, FU-rate 70–90%). Multivariate regression analyses were conducted to assess their effect on outcome. Two patient-reported outcome measures, Global Assessment of leg pain (GA) and the Oswestry Disability Index (ODI), as well as length of sick leave after surgery were analyzed.
Results
Clinical and socioeconomic factors significantly affected health outcome (both GA and ODI). Some predictors of a good outcome (ODI) were: being born in the EU, reporting no back pain at baseline, a high disposable income and a high educational level. Some factors predicting a worse outcome were previous surgery, having had back pain more than 2 years, having comorbidities, being a smoker, being on social welfare and being unemployed.
Conclusions
The study highlights the relevance of adding socioeconomic factors to clinical factors for analysis of patient-reported outcomes, although the causal pathway of most predictors’ impact is unknown. These findings should be further investigated in the perspective of treatment selection for individual LSS patients. The study also presents a foundation of case mix algorithms for predicting outcome of surgery for LSS.
Graphical abstract
These slides can be retrieved under Electronic Supplementary Material. |
doi_str_mv | 10.1007/s00586-018-5842-3 |
format | Article |
fullrecord | <record><control><sourceid>proquest_swepu</sourceid><recordid>TN_cdi_swepub_primary_oai_swepub_ki_se_483644</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2149863434</sourcerecordid><originalsourceid>FETCH-LOGICAL-c497t-ed838c715cb2a28ce35d2002968e388fdd5bba187de788e4205297d5f89c2fb3</originalsourceid><addsrcrecordid>eNp1kktv1DAUhSMEokPhB7BBlth0QcCvJDa7qjylSiBRsbUc-ya4TezBjlt1zw_HYaathDTe-PWd42v7VNVLgt8SjLt3CeNGtDUmom4EpzV7VG0IZ7TGktHH1QZLjuu2I_KoepbSJcakkbh9Wh0x3BBCOd9Uf75HsM4szo_ITM47oycU8mLCDEh7iybw4_ILhQElZ67KVF-XjWGBiFKOI8RbNISIpjz3uixtnS8GaQEfkkvIefTjBiz490ijOU-LqyOMLq1yuNZT1osL_nn1ZNBTghf7_ri6-PTx4uxLff7t89ez0_PacNktNVjBhOlIY3qqqTDAGksxprIVwIQYrG36XhPRWeiEAE5xQ2Vnm0FIQ4eeHVf1zjbdwDb3ahvdrOOtCtqp_dJVGYHigrWcF14e5Lcx2AfRnZBwUhpum6J9c1D7wf08VSGOKmfFhGzJip_s8OL7O0Na1OySgWnSHkJOihIuRcs4W6t6_R96GXIsr_6PEqUC2bWFIjvKxJBShOG-AoLVGh61C48q4VFreBQrmld759zPYO8Vd2kpAN1fqmz58vcPRx92_QvNfdJN</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2148411976</pqid></control><display><type>article</type><title>Predicting clinical outcome and length of sick leave after surgery for lumbar spinal stenosis in Sweden: a multi-register evaluation</title><source>SpringerNature Journals</source><creator>Iderberg, Hanna ; Willers, Carl ; Borgström, Fredrik ; Hedlund, Rune ; Hägg, Olle ; Möller, Hans ; Ornstein, Ewald ; Sandén, Bengt ; Stalberg, Holger ; Torevall-Larsson, Hans ; Tullberg, Tycho ; Fritzell, Peter</creator><creatorcontrib>Iderberg, Hanna ; Willers, Carl ; Borgström, Fredrik ; Hedlund, Rune ; Hägg, Olle ; Möller, Hans ; Ornstein, Ewald ; Sandén, Bengt ; Stalberg, Holger ; Torevall-Larsson, Hans ; Tullberg, Tycho ; Fritzell, Peter</creatorcontrib><description>Purpose
Lumbar spinal stenosis (LSS) can be surgically treated, with variable outcome. Studies have linked socioeconomic factors to outcome, but no nation-wide studies have been performed. This register-based study, including all patients surgically treated for LSS during 2008–2012 in Sweden, aimed to determine predictive factors for the outcome of surgery.
Methods
Clinical and socioeconomic factors with impact on outcome in LSS surgery were identified in several high-coverage registers, e.g., the national quality registry for spine surgery (Swespine, FU-rate 70–90%). Multivariate regression analyses were conducted to assess their effect on outcome. Two patient-reported outcome measures, Global Assessment of leg pain (GA) and the Oswestry Disability Index (ODI), as well as length of sick leave after surgery were analyzed.
Results
Clinical and socioeconomic factors significantly affected health outcome (both GA and ODI). Some predictors of a good outcome (ODI) were: being born in the EU, reporting no back pain at baseline, a high disposable income and a high educational level. Some factors predicting a worse outcome were previous surgery, having had back pain more than 2 years, having comorbidities, being a smoker, being on social welfare and being unemployed.
Conclusions
The study highlights the relevance of adding socioeconomic factors to clinical factors for analysis of patient-reported outcomes, although the causal pathway of most predictors’ impact is unknown. These findings should be further investigated in the perspective of treatment selection for individual LSS patients. The study also presents a foundation of case mix algorithms for predicting outcome of surgery for LSS.
Graphical abstract
These slides can be retrieved under Electronic Supplementary Material.</description><identifier>ISSN: 0940-6719</identifier><identifier>ISSN: 1432-0932</identifier><identifier>EISSN: 1432-0932</identifier><identifier>DOI: 10.1007/s00586-018-5842-3</identifier><identifier>PMID: 30511244</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Back pain ; Bone surgery ; Clinical outcomes ; Functional disability ; Global assessment ; Lumbar spinal stenosis ; Medicin och hälsovetenskap ; Medicine ; Medicine & Public Health ; Multi-register study ; Neurosurgery ; Original Article ; Pain ; Patient-reported outcome ; Patients ; Prediction algorithms ; Regression analysis ; Sick leave ; Socioeconomic factors ; Spinal stenosis ; Spine (lumbar) ; Spine surgery ; Surgery ; Surgical Orthopedics</subject><ispartof>European spine journal, 2019-06, Vol.28 (6), p.1423-1432</ispartof><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2018</rights><rights>European Spine Journal is a copyright of Springer, (2018). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c497t-ed838c715cb2a28ce35d2002968e388fdd5bba187de788e4205297d5f89c2fb3</citedby><cites>FETCH-LOGICAL-c497t-ed838c715cb2a28ce35d2002968e388fdd5bba187de788e4205297d5f89c2fb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00586-018-5842-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00586-018-5842-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,315,781,785,886,27929,27930,41493,42562,51324</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30511244$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-389615$$DView record from Swedish Publication Index$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:141111065$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Iderberg, Hanna</creatorcontrib><creatorcontrib>Willers, Carl</creatorcontrib><creatorcontrib>Borgström, Fredrik</creatorcontrib><creatorcontrib>Hedlund, Rune</creatorcontrib><creatorcontrib>Hägg, Olle</creatorcontrib><creatorcontrib>Möller, Hans</creatorcontrib><creatorcontrib>Ornstein, Ewald</creatorcontrib><creatorcontrib>Sandén, Bengt</creatorcontrib><creatorcontrib>Stalberg, Holger</creatorcontrib><creatorcontrib>Torevall-Larsson, Hans</creatorcontrib><creatorcontrib>Tullberg, Tycho</creatorcontrib><creatorcontrib>Fritzell, Peter</creatorcontrib><title>Predicting clinical outcome and length of sick leave after surgery for lumbar spinal stenosis in Sweden: a multi-register evaluation</title><title>European spine journal</title><addtitle>Eur Spine J</addtitle><addtitle>Eur Spine J</addtitle><description>Purpose
Lumbar spinal stenosis (LSS) can be surgically treated, with variable outcome. Studies have linked socioeconomic factors to outcome, but no nation-wide studies have been performed. This register-based study, including all patients surgically treated for LSS during 2008–2012 in Sweden, aimed to determine predictive factors for the outcome of surgery.
Methods
Clinical and socioeconomic factors with impact on outcome in LSS surgery were identified in several high-coverage registers, e.g., the national quality registry for spine surgery (Swespine, FU-rate 70–90%). Multivariate regression analyses were conducted to assess their effect on outcome. Two patient-reported outcome measures, Global Assessment of leg pain (GA) and the Oswestry Disability Index (ODI), as well as length of sick leave after surgery were analyzed.
Results
Clinical and socioeconomic factors significantly affected health outcome (both GA and ODI). Some predictors of a good outcome (ODI) were: being born in the EU, reporting no back pain at baseline, a high disposable income and a high educational level. Some factors predicting a worse outcome were previous surgery, having had back pain more than 2 years, having comorbidities, being a smoker, being on social welfare and being unemployed.
Conclusions
The study highlights the relevance of adding socioeconomic factors to clinical factors for analysis of patient-reported outcomes, although the causal pathway of most predictors’ impact is unknown. These findings should be further investigated in the perspective of treatment selection for individual LSS patients. The study also presents a foundation of case mix algorithms for predicting outcome of surgery for LSS.
Graphical abstract
These slides can be retrieved under Electronic Supplementary Material.</description><subject>Back pain</subject><subject>Bone surgery</subject><subject>Clinical outcomes</subject><subject>Functional disability</subject><subject>Global assessment</subject><subject>Lumbar spinal stenosis</subject><subject>Medicin och hälsovetenskap</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Multi-register study</subject><subject>Neurosurgery</subject><subject>Original Article</subject><subject>Pain</subject><subject>Patient-reported outcome</subject><subject>Patients</subject><subject>Prediction algorithms</subject><subject>Regression analysis</subject><subject>Sick leave</subject><subject>Socioeconomic factors</subject><subject>Spinal stenosis</subject><subject>Spine (lumbar)</subject><subject>Spine surgery</subject><subject>Surgery</subject><subject>Surgical Orthopedics</subject><issn>0940-6719</issn><issn>1432-0932</issn><issn>1432-0932</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kktv1DAUhSMEokPhB7BBlth0QcCvJDa7qjylSiBRsbUc-ya4TezBjlt1zw_HYaathDTe-PWd42v7VNVLgt8SjLt3CeNGtDUmom4EpzV7VG0IZ7TGktHH1QZLjuu2I_KoepbSJcakkbh9Wh0x3BBCOd9Uf75HsM4szo_ITM47oycU8mLCDEh7iybw4_ILhQElZ67KVF-XjWGBiFKOI8RbNISIpjz3uixtnS8GaQEfkkvIefTjBiz490ijOU-LqyOMLq1yuNZT1osL_nn1ZNBTghf7_ri6-PTx4uxLff7t89ez0_PacNktNVjBhOlIY3qqqTDAGksxprIVwIQYrG36XhPRWeiEAE5xQ2Vnm0FIQ4eeHVf1zjbdwDb3ahvdrOOtCtqp_dJVGYHigrWcF14e5Lcx2AfRnZBwUhpum6J9c1D7wf08VSGOKmfFhGzJip_s8OL7O0Na1OySgWnSHkJOihIuRcs4W6t6_R96GXIsr_6PEqUC2bWFIjvKxJBShOG-AoLVGh61C48q4VFreBQrmld759zPYO8Vd2kpAN1fqmz58vcPRx92_QvNfdJN</recordid><startdate>20190601</startdate><enddate>20190601</enddate><creator>Iderberg, Hanna</creator><creator>Willers, Carl</creator><creator>Borgström, Fredrik</creator><creator>Hedlund, Rune</creator><creator>Hägg, Olle</creator><creator>Möller, Hans</creator><creator>Ornstein, Ewald</creator><creator>Sandén, Bengt</creator><creator>Stalberg, Holger</creator><creator>Torevall-Larsson, Hans</creator><creator>Tullberg, Tycho</creator><creator>Fritzell, Peter</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>ADTPV</scope><scope>AOWAS</scope><scope>DF2</scope></search><sort><creationdate>20190601</creationdate><title>Predicting clinical outcome and length of sick leave after surgery for lumbar spinal stenosis in Sweden: a multi-register evaluation</title><author>Iderberg, Hanna ; Willers, Carl ; Borgström, Fredrik ; Hedlund, Rune ; Hägg, Olle ; Möller, Hans ; Ornstein, Ewald ; Sandén, Bengt ; Stalberg, Holger ; Torevall-Larsson, Hans ; Tullberg, Tycho ; Fritzell, Peter</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c497t-ed838c715cb2a28ce35d2002968e388fdd5bba187de788e4205297d5f89c2fb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Back pain</topic><topic>Bone surgery</topic><topic>Clinical outcomes</topic><topic>Functional disability</topic><topic>Global assessment</topic><topic>Lumbar spinal stenosis</topic><topic>Medicin och hälsovetenskap</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Multi-register study</topic><topic>Neurosurgery</topic><topic>Original Article</topic><topic>Pain</topic><topic>Patient-reported outcome</topic><topic>Patients</topic><topic>Prediction algorithms</topic><topic>Regression analysis</topic><topic>Sick leave</topic><topic>Socioeconomic factors</topic><topic>Spinal stenosis</topic><topic>Spine (lumbar)</topic><topic>Spine surgery</topic><topic>Surgery</topic><topic>Surgical Orthopedics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Iderberg, Hanna</creatorcontrib><creatorcontrib>Willers, Carl</creatorcontrib><creatorcontrib>Borgström, Fredrik</creatorcontrib><creatorcontrib>Hedlund, Rune</creatorcontrib><creatorcontrib>Hägg, Olle</creatorcontrib><creatorcontrib>Möller, Hans</creatorcontrib><creatorcontrib>Ornstein, Ewald</creatorcontrib><creatorcontrib>Sandén, Bengt</creatorcontrib><creatorcontrib>Stalberg, Holger</creatorcontrib><creatorcontrib>Torevall-Larsson, Hans</creatorcontrib><creatorcontrib>Tullberg, Tycho</creatorcontrib><creatorcontrib>Fritzell, Peter</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>SwePub</collection><collection>SwePub Articles</collection><collection>SWEPUB Uppsala universitet</collection><jtitle>European spine journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Iderberg, Hanna</au><au>Willers, Carl</au><au>Borgström, Fredrik</au><au>Hedlund, Rune</au><au>Hägg, Olle</au><au>Möller, Hans</au><au>Ornstein, Ewald</au><au>Sandén, Bengt</au><au>Stalberg, Holger</au><au>Torevall-Larsson, Hans</au><au>Tullberg, Tycho</au><au>Fritzell, Peter</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Predicting clinical outcome and length of sick leave after surgery for lumbar spinal stenosis in Sweden: a multi-register evaluation</atitle><jtitle>European spine journal</jtitle><stitle>Eur Spine J</stitle><addtitle>Eur Spine J</addtitle><date>2019-06-01</date><risdate>2019</risdate><volume>28</volume><issue>6</issue><spage>1423</spage><epage>1432</epage><pages>1423-1432</pages><issn>0940-6719</issn><issn>1432-0932</issn><eissn>1432-0932</eissn><abstract>Purpose
Lumbar spinal stenosis (LSS) can be surgically treated, with variable outcome. Studies have linked socioeconomic factors to outcome, but no nation-wide studies have been performed. This register-based study, including all patients surgically treated for LSS during 2008–2012 in Sweden, aimed to determine predictive factors for the outcome of surgery.
Methods
Clinical and socioeconomic factors with impact on outcome in LSS surgery were identified in several high-coverage registers, e.g., the national quality registry for spine surgery (Swespine, FU-rate 70–90%). Multivariate regression analyses were conducted to assess their effect on outcome. Two patient-reported outcome measures, Global Assessment of leg pain (GA) and the Oswestry Disability Index (ODI), as well as length of sick leave after surgery were analyzed.
Results
Clinical and socioeconomic factors significantly affected health outcome (both GA and ODI). Some predictors of a good outcome (ODI) were: being born in the EU, reporting no back pain at baseline, a high disposable income and a high educational level. Some factors predicting a worse outcome were previous surgery, having had back pain more than 2 years, having comorbidities, being a smoker, being on social welfare and being unemployed.
Conclusions
The study highlights the relevance of adding socioeconomic factors to clinical factors for analysis of patient-reported outcomes, although the causal pathway of most predictors’ impact is unknown. These findings should be further investigated in the perspective of treatment selection for individual LSS patients. The study also presents a foundation of case mix algorithms for predicting outcome of surgery for LSS.
Graphical abstract
These slides can be retrieved under Electronic Supplementary Material.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>30511244</pmid><doi>10.1007/s00586-018-5842-3</doi><tpages>10</tpages></addata></record> |
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source | SpringerNature Journals |
subjects | Back pain Bone surgery Clinical outcomes Functional disability Global assessment Lumbar spinal stenosis Medicin och hälsovetenskap Medicine Medicine & Public Health Multi-register study Neurosurgery Original Article Pain Patient-reported outcome Patients Prediction algorithms Regression analysis Sick leave Socioeconomic factors Spinal stenosis Spine (lumbar) Spine surgery Surgery Surgical Orthopedics |
title | Predicting clinical outcome and length of sick leave after surgery for lumbar spinal stenosis in Sweden: a multi-register evaluation |
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