Identification and prospective stability of electronic nose (eNose)–derived inflammatory phenotypes in patients with severe asthma

Severe asthma is a heterogeneous condition, as shown by independent cluster analyses based on demographic, clinical, and inflammatory characteristics. A next step is to identify molecularly driven phenotypes using “omics” technologies. Molecular fingerprints of exhaled breath are associated with inf...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of allergy and clinical immunology 2019-05, Vol.143 (5), p.1811-1820.e7
Hauptverfasser:	Brinkman, Paul, Wagener, Ariane H., Hekking, Pieter-Paul, Bansal, Aruna T., Maitland-van der Zee, Anke-Hilse, Wang, Yuanyue, Weda, Hans, Knobel, Hugo H., Vink, Teunis J., Rattray, Nicholas J., D'Amico, Arnaldo, Pennazza, Giorgio, Santonico, Marco, Lefaudeux, Diane, De Meulder, Bertrand, Auffray, Charles, Bakke, Per S., Caruso, Massimo, Chanez, Pascal, Chung, Kian F., Corfield, Julie, Dahlén, Sven-Erik, Djukanovic, Ratko, Geiser, Thomas, Horvath, Ildiko, Krug, Nobert, Musial, Jacek, Sun, Kai, Riley, John H., Shaw, Dominic E., Sandström, Thomas, Sousa, Ana R., Montuschi, Paolo, Fowler, Stephen J., Sterk, Peter J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Asthma Asthma - diagnosis Biomarkers Body mass index Breath Tests Chemical fingerprinting Chronic obstructive pulmonary disease Cluster Analysis Cohort Studies Corticoids Corticosteroids Demographics Disease Progression Electronic Nose Electronic nose technology Electronic noses eosinophils Eosinophils - pathology Exhalation exhaled breath Female follow-up Follow-Up Studies Gene expression Humans Independent study Inflammation Inflammation - diagnosis Leukocytes (eosinophilic) Male Metabolites Metabolomics Middle Aged Neutrophils Neutrophils - pathology oral corticosteroids Patients Pattern recognition Phenotype Phenotypes severe asthma Severity of Illness Index Sputum Steroids unbiased clustering volatile organic compound
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!