Tracking Pore Hydration in Channelrhodopsin by Site-Directed Infrared-Active Azido Probes

In recent years, gating and transient ion-pathway formation in the light-gated channelrhodopsins (ChRs) have been intensively studied. Despite these efforts, a profound understanding of the mechanistic details is still lacking. To track structural changes concomitant with the formation and subsequen...

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Veröffentlicht in:Biochemistry (Easton) 2019-03, Vol.58 (9), p.1275-1286
Hauptverfasser: Krause, Benjamin S, Kaufmann, Joel C. D, Kuhne, Jens, Vierock, Johannes, Huber, Thomas, Sakmar, Thomas P, Gerwert, Klaus, Bartl, Franz J, Hegemann, Peter
Format: Artikel
Sprache:eng
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