Powerful Homeostatic Control of Oligodendroglial Lineage by PDGFRα in Adult Brain

Oligodendrocyte progenitor cells (OPCs) are widely distributed cells of ramified morphology in adult brain that express PDGFRα and NG2. They retain mitotic activities in adulthood and contribute to oligodendrogenesis and myelin turnover; however, the regulatory mechanisms of their cell dynamics in a...

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Veröffentlicht in:	Cell reports (Cambridge) 2019-04, Vol.27 (4), p.1073-1089.e5
Hauptverfasser:	Đặng, Thành Chung, Ishii, Yoko, Nguyen, Van De, Yamamoto, Seiji, Hamashima, Takeru, Okuno, Noriko, Nguyen, Quang Linh, Sang, Yang, Ohkawa, Noriaki, Saitoh, Yoshito, Shehata, Mohammad, Takakura, Nobuyuki, Fujimori, Toshihiko, Inokuchi, Kaoru, Mori, Hisashi, Andrae, Johanna, Betsholtz, Christer, Sasahara, Masakiyo
Format:	Artikel
Sprache:	eng
Schlagworte:	adult brain differentiation mesenchymal cell oligodendrocyte progenitor cell PDGFRα pericyte regeneration
Online-Zugang:	Volltext
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