Effect of Trans-Nasal Evaporative Intra-arrest Cooling on Functional Neurologic Outcome in Out-of-Hospital Cardiac Arrest: The PRINCESS Randomized Clinical Trial

IMPORTANCE: Therapeutic hypothermia may increase survival with good neurologic outcome after cardiac arrest. Trans-nasal evaporative cooling is a method used to induce cooling, primarily of the brain, during cardiopulmonary resuscitation (ie, intra-arrest). OBJECTIVE: To determine whether prehospita...

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Veröffentlicht in:	JAMA : the journal of the American Medical Association 2019-05, Vol.321 (17), p.1677-1685
Hauptverfasser:	Nordberg, Per, Taccone, Fabio Silvio, Truhlar, Anatolij, Forsberg, Sune, Hollenberg, Jacob, Jonsson, Martin, Cuny, Jerome, Goldstein, Patrick, Vermeersch, Nick, Higuet, Adeline, Jiménes, Francisco Carmona, Ortiz, Fernando Rosell, Williams, Julia, Desruelles, Didier, Creteur, Jacques, Dillenbeck, Emelie, Busche, Caroline, Busch, Hans-Jörg, Ringh, Mattias, Konrad, David, Peterson, Johan, Vincent, Jean-Louis, Svensson, Leif
Format:	Artikel
Sprache:	eng
Schlagworte:	Body temperature Brain Cardiac arrest Cardiopulmonary resuscitation Caring for the Critically Ill Patient Clinical trials Cooling CPR Emergency medical services Evaporative cooling Health risk assessment Heart Hypothermia Intervention Original Investigation Patients Resuscitation Statistical analysis Survival
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