Persistent emotional distress after a first-time myocardial infarction and its association to late cardiovascular and non-cardiovascular mortality

Background Patients with symptoms of depression and/or anxiety – emotional distress – after a myocardial infarction (MI) have been shown to have worse prognosis and increased healthcare costs. However, whether specific subgroups of patients with emotional distress are more vulnerable is less well es...

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Veröffentlicht in:European journal of preventive cardiology 2019-09, Vol.26 (14), p.1510-1518
Hauptverfasser: Lissåker, Claudia T, Norlund, Fredrika, Wallert, John, Held, Claes, Olsson, Erik MG
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container_issue 14
container_start_page 1510
container_title European journal of preventive cardiology
container_volume 26
creator Lissåker, Claudia T
Norlund, Fredrika
Wallert, John
Held, Claes
Olsson, Erik MG
description Background Patients with symptoms of depression and/or anxiety – emotional distress – after a myocardial infarction (MI) have been shown to have worse prognosis and increased healthcare costs. However, whether specific subgroups of patients with emotional distress are more vulnerable is less well established. The purpose of this study was to identify the association between different patterns of emotional distress over time with late cardiovascular and non-cardiovascular mortality among first-MI patients aged
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However, whether specific subgroups of patients with emotional distress are more vulnerable is less well established. The purpose of this study was to identify the association between different patterns of emotional distress over time with late cardiovascular and non-cardiovascular mortality among first-MI patients aged &lt;75 years in Sweden. Methods We utilized data on 57,602 consecutive patients with a first-time MI from the national SWEDEHEART registers. Emotional distress was assessed using the anxiety/depression dimension of the European Quality of Life Five Dimensions questionnaire two and 12 months after the MI, combined into persistent (emotional distress at both time-points), remittent (emotional distress at the first follow-up only), new (emotional distress at the second-follow up only) or no distress. Data on cardiovascular and non-cardiovascular mortality were obtained until the study end-time. We used multiple imputation to create complete datasets and adjusted Cox proportional hazards models to estimate hazard ratios. Results Patients with persistent emotional distress were more likely to die from cardiovascular (hazard ratio: 1.46, 95% confidence interval: 1.16, 1.84) and non-cardiovascular causes (hazard ratio: 1.54, 95% confidence interval: 1.30, 1.82) than those with no distress. Those with remittent emotional distress were not statistically significantly more likely to die from any cause than those without emotional distress. Discussion Among patients who survive 12 months, persistent, but not remittent, emotional distress was associated with increased cardiovascular and non-cardiovascular mortality. This indicates a need to identify subgroups of individuals with emotional distress who may benefit from further assessment and specific treatment.</description><identifier>ISSN: 2047-4873</identifier><identifier>EISSN: 2047-4881</identifier><identifier>DOI: 10.1177/2047487319841475</identifier><identifier>PMID: 31159570</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Aged ; Cause of Death ; Female ; Humans ; Male ; Middle Aged ; Myocardial Infarction - diagnosis ; Myocardial Infarction - mortality ; Myocardial Infarction - psychology ; Prognosis ; Psychological Distress ; Registries ; Risk Assessment ; Risk Factors ; Stress, Psychological - diagnosis ; Stress, Psychological - mortality ; Stress, Psychological - psychology ; Sweden - epidemiology ; Time Factors</subject><ispartof>European journal of preventive cardiology, 2019-09, Vol.26 (14), p.1510-1518</ispartof><rights>The European Society of Cardiology 2019</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-caba4a098f8ea79118d661cafa8300a5726988187663887a29d79b899ae8a4b73</citedby><cites>FETCH-LOGICAL-c375t-caba4a098f8ea79118d661cafa8300a5726988187663887a29d79b899ae8a4b73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/2047487319841475$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/2047487319841475$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>230,314,776,780,881,21798,27901,27902,43597,43598</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31159570$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:141675284$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Lissåker, Claudia T</creatorcontrib><creatorcontrib>Norlund, Fredrika</creatorcontrib><creatorcontrib>Wallert, John</creatorcontrib><creatorcontrib>Held, Claes</creatorcontrib><creatorcontrib>Olsson, Erik MG</creatorcontrib><title>Persistent emotional distress after a first-time myocardial infarction and its association to late cardiovascular and non-cardiovascular mortality</title><title>European journal of preventive cardiology</title><addtitle>Eur J Cardiovasc Prev Rehabil</addtitle><description>Background Patients with symptoms of depression and/or anxiety – emotional distress – after a myocardial infarction (MI) have been shown to have worse prognosis and increased healthcare costs. However, whether specific subgroups of patients with emotional distress are more vulnerable is less well established. The purpose of this study was to identify the association between different patterns of emotional distress over time with late cardiovascular and non-cardiovascular mortality among first-MI patients aged &lt;75 years in Sweden. Methods We utilized data on 57,602 consecutive patients with a first-time MI from the national SWEDEHEART registers. Emotional distress was assessed using the anxiety/depression dimension of the European Quality of Life Five Dimensions questionnaire two and 12 months after the MI, combined into persistent (emotional distress at both time-points), remittent (emotional distress at the first follow-up only), new (emotional distress at the second-follow up only) or no distress. Data on cardiovascular and non-cardiovascular mortality were obtained until the study end-time. We used multiple imputation to create complete datasets and adjusted Cox proportional hazards models to estimate hazard ratios. Results Patients with persistent emotional distress were more likely to die from cardiovascular (hazard ratio: 1.46, 95% confidence interval: 1.16, 1.84) and non-cardiovascular causes (hazard ratio: 1.54, 95% confidence interval: 1.30, 1.82) than those with no distress. Those with remittent emotional distress were not statistically significantly more likely to die from any cause than those without emotional distress. Discussion Among patients who survive 12 months, persistent, but not remittent, emotional distress was associated with increased cardiovascular and non-cardiovascular mortality. This indicates a need to identify subgroups of individuals with emotional distress who may benefit from further assessment and specific treatment.</description><subject>Aged</subject><subject>Cause of Death</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Myocardial Infarction - diagnosis</subject><subject>Myocardial Infarction - mortality</subject><subject>Myocardial Infarction - psychology</subject><subject>Prognosis</subject><subject>Psychological Distress</subject><subject>Registries</subject><subject>Risk Assessment</subject><subject>Risk Factors</subject><subject>Stress, Psychological - diagnosis</subject><subject>Stress, Psychological - mortality</subject><subject>Stress, Psychological - psychology</subject><subject>Sweden - epidemiology</subject><subject>Time Factors</subject><issn>2047-4873</issn><issn>2047-4881</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kc1q3TAQhUVJaEKSfVdBy27cSpZtScsSmqQQSBfNWoztcVBqWzcaOeW-Rp64uj-9hEBnM8PhOwehw9gnKb5IqfXXUlS6MlpJaypZ6foDO91IRWWMPDrcWp2wC6InkacRZWnMR3aipKxtrcUpe_2JkTwlnBPHKSQfZhh5n5WIRByGhJEDH3ykVCQ_IZ_WoYPY-4z5eYDYbTwc5p77lA1EofOw1VLgIyTkWzy8AHXLCHGLzmEu3slTiAlGn9bn7HiAkfBiv8_Yw_X3X1e3xd39zY-rb3dFp3Sdsr2FCoQ1g0HQVkrTN43sYACjhIBal43NP2F00yhjNJS217Y11gIaqFqtzlixy6U_uFpat4p-grh2AbzbS7_zha7SVmmZ-c87fhXD84KU3OSpw3GEGcNCrixVLRotjMmo2KFdDEQRh0O4FG5TnntfXrZc7tOXdsL-YPhX1ZvnwiO6p7DE3BT9P_Av0GilOA</recordid><startdate>20190901</startdate><enddate>20190901</enddate><creator>Lissåker, Claudia T</creator><creator>Norlund, Fredrika</creator><creator>Wallert, John</creator><creator>Held, Claes</creator><creator>Olsson, Erik MG</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>ADTPV</scope><scope>AOWAS</scope></search><sort><creationdate>20190901</creationdate><title>Persistent emotional distress after a first-time myocardial infarction and its association to late cardiovascular and non-cardiovascular mortality</title><author>Lissåker, Claudia T ; Norlund, Fredrika ; Wallert, John ; Held, Claes ; Olsson, Erik MG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-caba4a098f8ea79118d661cafa8300a5726988187663887a29d79b899ae8a4b73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Aged</topic><topic>Cause of Death</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Myocardial Infarction - diagnosis</topic><topic>Myocardial Infarction - mortality</topic><topic>Myocardial Infarction - psychology</topic><topic>Prognosis</topic><topic>Psychological Distress</topic><topic>Registries</topic><topic>Risk Assessment</topic><topic>Risk Factors</topic><topic>Stress, Psychological - diagnosis</topic><topic>Stress, Psychological - mortality</topic><topic>Stress, Psychological - psychology</topic><topic>Sweden - epidemiology</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lissåker, Claudia T</creatorcontrib><creatorcontrib>Norlund, Fredrika</creatorcontrib><creatorcontrib>Wallert, John</creatorcontrib><creatorcontrib>Held, Claes</creatorcontrib><creatorcontrib>Olsson, Erik MG</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>SwePub</collection><collection>SwePub Articles</collection><jtitle>European journal of preventive cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lissåker, Claudia T</au><au>Norlund, Fredrika</au><au>Wallert, John</au><au>Held, Claes</au><au>Olsson, Erik MG</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Persistent emotional distress after a first-time myocardial infarction and its association to late cardiovascular and non-cardiovascular mortality</atitle><jtitle>European journal of preventive cardiology</jtitle><addtitle>Eur J Cardiovasc Prev Rehabil</addtitle><date>2019-09-01</date><risdate>2019</risdate><volume>26</volume><issue>14</issue><spage>1510</spage><epage>1518</epage><pages>1510-1518</pages><issn>2047-4873</issn><eissn>2047-4881</eissn><abstract>Background Patients with symptoms of depression and/or anxiety – emotional distress – after a myocardial infarction (MI) have been shown to have worse prognosis and increased healthcare costs. However, whether specific subgroups of patients with emotional distress are more vulnerable is less well established. The purpose of this study was to identify the association between different patterns of emotional distress over time with late cardiovascular and non-cardiovascular mortality among first-MI patients aged &lt;75 years in Sweden. Methods We utilized data on 57,602 consecutive patients with a first-time MI from the national SWEDEHEART registers. Emotional distress was assessed using the anxiety/depression dimension of the European Quality of Life Five Dimensions questionnaire two and 12 months after the MI, combined into persistent (emotional distress at both time-points), remittent (emotional distress at the first follow-up only), new (emotional distress at the second-follow up only) or no distress. Data on cardiovascular and non-cardiovascular mortality were obtained until the study end-time. We used multiple imputation to create complete datasets and adjusted Cox proportional hazards models to estimate hazard ratios. Results Patients with persistent emotional distress were more likely to die from cardiovascular (hazard ratio: 1.46, 95% confidence interval: 1.16, 1.84) and non-cardiovascular causes (hazard ratio: 1.54, 95% confidence interval: 1.30, 1.82) than those with no distress. Those with remittent emotional distress were not statistically significantly more likely to die from any cause than those without emotional distress. Discussion Among patients who survive 12 months, persistent, but not remittent, emotional distress was associated with increased cardiovascular and non-cardiovascular mortality. This indicates a need to identify subgroups of individuals with emotional distress who may benefit from further assessment and specific treatment.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>31159570</pmid><doi>10.1177/2047487319841475</doi><tpages>9</tpages></addata></record>
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source Oxford University Press Journals All Titles (1996-Current); MEDLINE; SAGE Complete; Alma/SFX Local Collection
subjects Aged
Cause of Death
Female
Humans
Male
Middle Aged
Myocardial Infarction - diagnosis
Myocardial Infarction - mortality
Myocardial Infarction - psychology
Prognosis
Psychological Distress
Registries
Risk Assessment
Risk Factors
Stress, Psychological - diagnosis
Stress, Psychological - mortality
Stress, Psychological - psychology
Sweden - epidemiology
Time Factors
title Persistent emotional distress after a first-time myocardial infarction and its association to late cardiovascular and non-cardiovascular mortality
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