Neutralization of the Positive Charges on Histone Tails by RNA Promotes an Open Chromatin Structure

RNA associates extensively with chromatin and can influence its structure; however, the potential role of the negative charges of RNA on chromatin structure remains unknown. Here, we demonstrate that RNA prevents precipitation of histones and can attenuate electrostatic interactions between histones...

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Veröffentlicht in:	CELL CHEMICAL BIOLOGY 2019-10, Vol.26 (10), p.1436-1449.e5
Hauptverfasser:	Dueva, Rositsa, Akopyan, Karen, Pederiva, Chiara, Trevisan, Davide, Dhanjal, Soniya, Lindqvist, Arne, Farnebo, Marianne
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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