Validity and reliability of extrastriatal [11C]raclopride binding quantification in the living human brain

[11C]raclopride is a well established PET tracer for the quantification of dopamine 2/3 receptors (D2/3R) in the striatum. Outside of the striatum the receptor density is up to two orders of magnitude lower. In contrast to striatal binding, the characteristics of extrastriatal [11C]raclopride bindin...

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Veröffentlicht in:	NeuroImage (Orlando, Fla.) Fla.), 2019-11, Vol.202, p.116143-116143, Article 116143
Hauptverfasser:	Svensson, Jonas E., Schain, Martin, Plavén-Sigray, Pontus, Cervenka, Simon, Tiger, Mikael, Nord, Magdalena, Halldin, Christer, Farde, Lars, Lundberg, Johan
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain research Cerebellum Competition Cortex (frontal) Cortex (temporal) Dopamine Dopamine D2 receptors Drug dosages Experiments Extrastriatal Medicin och hälsovetenskap Neostriatum NMR Nuclear magnetic resonance Occupancy Positron emission tomography Putamen Quetiapine Raclopride Receptor density Reference region Thalamus Validity
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