TREM-1 Is Upregulated in Experimental Periodontitis, and Its Blockade Inhibits IL-17A and RANKL Expression and Suppresses Bone loss

Aim: Triggering receptor expressed on myeloid cells-1 (TREM-1) is a modifier of local and systemic inflammation. There is clinical evidence implicating TREM-1 in the pathogenesis of periodontitis. However, a cause-and-effect relationship has yet to be demonstrated, as is the underlying mechanism. Th...

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Veröffentlicht in:	JOURNAL OF CLINICAL MEDICINE 2019-10, Vol.8 (10), p.1579
Hauptverfasser:	Bostanci, Nagihan, Abe, Toshiharu, Belibasakis, Georgios N., Hajishengallis, George
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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