miR-124/VAMP3 is a novel therapeutic target for mitigation of surgical trauma-induced microglial activation

Activation of microglia and the subsequently elevated inflammatory cytokine release in the brain during surgery predispose individuals to cognitive dysfunction, also known as postoperative cognitive dysfunction (POCD). miR-124 is one of the most abundant microRNAs in the brain that regulates microgl...

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Veröffentlicht in:	SIGNAL TRANSDUCTION AND TARGETED THERAPY 2019-08, Vol.4 (1), p.27-11, Article 27
Hauptverfasser:	Chen, Yan, Sun, Jing-xian, Chen, Wan-kun, Wu, Gen-cheng, Wang, Yan-qing, Zhu, Ke-ying, Wang, Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	631/250/249 631/378/371 692/308/1426 Cancer Research Cell Biology Cytokines Internal Medicine Medicine Medicine & Public Health Oncology Pathology Surgery
Online-Zugang:	Volltext
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