Characterization of Single Gene Copy Number Variants in Schizophrenia

Genetic studies of schizophrenia have implicated numerous risk loci including several copy number variants (CNVs) of large effect and hundreds of loci of small effect. In only a few cases has a specific gene been clearly identified. Rare CNVs affecting a single gene offer a potential avenue to disco...

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Veröffentlicht in:	Biological psychiatry (1969) 2020-04, Vol.87 (8), p.736-744
Hauptverfasser:	Szatkiewicz, Jin P., Fromer, Menachem, Nonneman, Randal J., Ancalade, NaEshia, Johnson, Jessica S., Stahl, Eli A., Rees, Elliott, Bergen, Sarah E., Hultman, Christina M., Kirov, George, O’Donovan, Michael, Owen, Michael, Holmans, Peter, Sklar, Pamela, Sullivan, Patrick F., Purcell, Shaun M., Crowley, James J., Ruderfer, Douglas M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcium channel Copy number variation DNA Copy Number Variations - genetics Exome sequencing Exons Gene Dosage Genetic Predisposition to Disease Genetics Humans Schizophrenia Schizophrenia - genetics Single gene Sweden
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