Intraductal carcinoma of the prostate is an aggressive form of invasive carcinoma and should be graded
Infiltration of the prostatic ducts by prostatic adenocarcinoma occurs relatively frequently, being most commonly associated with high grade disease. It is now recognised that intraductal carcinoma of the prostate (IDCP) has an associated poor prognosis and this is reflected in its histological, mol...
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Veröffentlicht in: | Pathology 2020-02, Vol.52 (2), p.192-196 |
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creator | Samaratunga, Hemamali Delahunt, Brett Egevad, Lars Srigley, John R. Billis, Athanase Bostwick, David G. Camparo, Philippe Cheng, Liang Clouston, David Denham, James Furusato, Bungo Hartmann, Arndt Jufe, Laura Kench, James Kenwright, Diane N. Kristiansen, Glen Leite, Katia R.M. MacLennan, Gregory T. Merrimen, Jennifer Moch, Holger Oxley, Jon Pan, Chin-Chen Paner, Gladell Ro, Jae Sesterhenn, Isabell A.M. Shanks, Jonathan Thunders, Michelle Tsuzuki, Toyonori Wheeler, Thomas Yaxley, John W. Varma, Murali |
description | Infiltration of the prostatic ducts by prostatic adenocarcinoma occurs relatively frequently, being most commonly associated with high grade disease. It is now recognised that intraductal carcinoma of the prostate (IDCP) has an associated poor prognosis and this is reflected in its histological, molecular and immunohistochemical features. The current recommendation of the World Health Organization is that IDCP not be taken into consideration when grading prostate adenocarcinoma. It is apparent that Gleason did not differentiate between IDCP and stromal invasive carcinoma when developing and validating his grading system, and recent studies suggest that the incorporation of IDCP grading into the overall grading of the specimen provides additional prognostic information. |
doi_str_mv | 10.1016/j.pathol.2019.11.001 |
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It is now recognised that intraductal carcinoma of the prostate (IDCP) has an associated poor prognosis and this is reflected in its histological, molecular and immunohistochemical features. The current recommendation of the World Health Organization is that IDCP not be taken into consideration when grading prostate adenocarcinoma. It is apparent that Gleason did not differentiate between IDCP and stromal invasive carcinoma when developing and validating his grading system, and recent studies suggest that the incorporation of IDCP grading into the overall grading of the specimen provides additional prognostic information.</description><identifier>ISSN: 0031-3025</identifier><identifier>EISSN: 1465-3931</identifier><identifier>DOI: 10.1016/j.pathol.2019.11.001</identifier><identifier>PMID: 31843189</identifier><language>eng</language><publisher>England: Elsevier B.V</publisher><subject>intraductal carcinoma of prostate ; ISUP grade ; prognosis ; Prostate adenocarcinoma</subject><ispartof>Pathology, 2020-02, Vol.52 (2), p.192-196</ispartof><rights>2019 Royal College of Pathologists of Australasia</rights><rights>Copyright © 2019 Royal College of Pathologists of Australasia. 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It is now recognised that intraductal carcinoma of the prostate (IDCP) has an associated poor prognosis and this is reflected in its histological, molecular and immunohistochemical features. The current recommendation of the World Health Organization is that IDCP not be taken into consideration when grading prostate adenocarcinoma. 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It is now recognised that intraductal carcinoma of the prostate (IDCP) has an associated poor prognosis and this is reflected in its histological, molecular and immunohistochemical features. The current recommendation of the World Health Organization is that IDCP not be taken into consideration when grading prostate adenocarcinoma. 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language | eng |
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source | Alma/SFX Local Collection |
subjects | intraductal carcinoma of prostate ISUP grade prognosis Prostate adenocarcinoma |
title | Intraductal carcinoma of the prostate is an aggressive form of invasive carcinoma and should be graded |
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