Neutrophil Extracellular Traps Participate in Cardiovascular Diseases: Recent Experimental and Clinical Insights

Neutrophil extracellular traps (NETs) have recently emerged as a newly recognized contributor to venous and arterial thrombosis. These strands of DNA extruded by activated or dying neutrophils, decorated with various protein mediators, become solid-state reactors that can localize at the critical in...

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Veröffentlicht in:	CIRCULATION RESEARCH 2020-04, Vol.126 (9), p.1228-1241
Hauptverfasser:	Döring, Yvonne, Libby, Peter, Soehnlein, Oliver
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arteries - immunology Arteries - metabolism Arteries - pathology Atherosclerosis - immunology Atherosclerosis - metabolism Atherosclerosis - pathology Biomarkers - metabolism Blood Coagulation Extracellular Traps - immunology Extracellular Traps - metabolism Humans Inflammation - immunology Inflammation - metabolism Inflammation - pathology Inflammation Mediators - metabolism Neutrophils - immunology Neutrophils - metabolism Neutrophils - pathology Plaque, Atherosclerotic Reactive Oxygen Species - metabolism Rupture, Spontaneous Signal Transduction Thrombosis - immunology Thrombosis - metabolism Thrombosis - pathology
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