A randomized placebo-controlled PET study of ketamine´s effect on serotonin 1B receptor binding in patients with SSRI-resistant depression

The glutamate N-methyl-D-aspartate receptor antagonist ketamine has a rapid antidepressant effect. Despite large research efforts, ketamine's mechanism of action in major depressive disorder (MDD) has still not been determined. In rodents, the antidepressant properties of ketamine were found to...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Translational psychiatry 2020-06, Vol.10 (1), p.159
Hauptverfasser:	Tiger, Mikael, Veldman, Emma R, Ekman, Carl-Johan, Halldin, Christer, Svenningsson, Per, Lundberg, Johan
Format:	Artikel
Sprache:	eng
Schlagworte:	Depression Depressive Disorder, Major - diagnostic imaging Depressive Disorder, Major - drug therapy Humans Ketamine Positron-Emission Tomography Receptor, Serotonin, 5-HT1B Serotonin Serotonin Uptake Inhibitors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!