Immunological and behavioral responses to in vivo lipopolysaccharide administration in young and healthy obese and normal-weight humans

•The behavioral responses to LPS was similar in obese and normal-weight subjects.•The cortisol response to LPS was attenuated in obese individuals and related to body fat.•Obesity per se is not associated with increased behavioral sensitivity to cytokines.•The hypothalamus functions might be disrupt...

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