Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind, randomised, placebo-controlled trial

Lynch syndrome is associated with an increased risk of colorectal cancer and with a broader spectrum of cancers, especially endometrial cancer. In 2011, our group reported long-term cancer outcomes (mean follow-up 55·7 months [SD 31·4]) for participants with Lynch syndrome enrolled into a randomised...

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Veröffentlicht in:The Lancet (British edition) 2020-06, Vol.395 (10240), p.1855-1863
Hauptverfasser: Burn, John, Sheth, Harsh, Elliott, Faye, Reed, Lynn, Macrae, Finlay, Mecklin, Jukka-Pekka, Möslein, Gabriela, McRonald, Fiona E, Bertario, Lucio, Evans, D Gareth, Gerdes, Anne-Marie, Ho, Judy W C, Lindblom, Annika, Morrison, Patrick J, Rashbass, Jem, Ramesar, Raj, Seppälä, Toni, Thomas, Huw J W, Pylvänäinen, Kirsi, Borthwick, Gillian M, Mathers, John C, Bishop, D Timothy, Boussioutas, Alex, Brewer, Carole, Cook, Jackie, Eccles, Diana, Ellis, Anthony, Hodgson, Shirley V, Lubinski, Jan, Maher, Eamonn R, Porteous, Mary EM, Sampson, Julian, Scott, Rodney J, Side, Lucy
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Sprache:eng
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