A new house dust mite–driven and mast cell–activated model of asthma in the guinea pig

Background Animal models are extensively used to study underlying mechanisms in asthma. Guinea pigs share anatomical, pharmacological and physiological features with human airways and may enable the development of a pre‐clinical in vivo model that closely resembles asthma. Objectives To develop an a...

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Veröffentlicht in:	Clinical and experimental allergy 2020-10, Vol.50 (10), p.1184-1195
Hauptverfasser:	Ramos‐Ramírez, Patricia, Noreby, Malin, Liu, Jielu, Ji, Jie, Abdillahi, Suado M., Olsson, Henric, Dahlén, Sven‐Erik, Nilsson, Gunnar, Adner, Mikael
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergens Allergy Alveoli Animal models Asthma Bronchoconstriction Bronchus Cell activation Collagen Enzyme-linked immunosorbent assay Eosinophilia Histamine Hyperplasia Immunoglobulin E Immunoglobulin G Immunology Inflammation Leukotrienes Life Sciences & Biomedicine Mast cells Medicin och hälsovetenskap Methacholine Prostaglandins Respiration Respiratory tract Science & Technology
Online-Zugang:	Volltext
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