Low‐dose hydrocortisone in patients with COVID‐19 and severe hypoxia (COVID STEROID) trial—Protocol and statistical analysis plan

Introduction Severe acute respiratory syndrome coronavirus‐2 has caused a pandemic of coronavirus disease (COVID‐19) with many patients developing hypoxic respiratory failure. Corticosteroids reduce the time on mechanical ventilation, length of stay in the intensive care unit and potentially also mo...

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Veröffentlicht in:	Acta anaesthesiologica Scandinavica 2020-10, Vol.64 (9), p.1365-1375
Hauptverfasser:	Petersen, Marie Warrer, Meyhoff, Tine Sylvest, Helleberg, Marie, Kjær, Maj‐Brit Nørregaard, Granholm, Anders, Hjortsø, Carl Johan Steensen, Jensen, Thomas Steen, Møller, Morten Hylander, Hjortrup, Peter Buhl, Wetterslev, Mik, Vesterlund, Gitte Kingo, Russell, Lene, Jørgensen, Vibeke Lind, Tjelle, Klaus, Benfield, Thomas, Ulrik, Charlotte Suppli, Andreasen, Anne Sofie, Mohr, Thomas, Bestle, Morten H., Poulsen, Lone Musaeus, Hitz, Mette Friberg, Hildebrandt, Thomas, Knudsen, Lene Surland, Møller, Anders, Sølling, Christoffer Grant, Brøchner, Anne Craveiro, Rasmussen, Bodil Steen, Nielsen, Henrik, Christensen, Steffen, Strøm, Thomas, Cronhjort, Maria, Wahlin, Rebecka Rubenson, Jakob, Stephan, Cioccari, Luca, Venkatesh, Balasubramanian, Hammond, Naomi, Jha, Vivekanand, Myatra, Sheila Nainan, Gluud, Christian, Lange, Theis, Perner, Anders
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-Inflammatory Agents - therapeutic use Clinical trials Confidence intervals Coronaviridae Coronaviruses Corticoids Corticosteroids COVID-19 COVID-19 - complications COVID-19 Drug Treatment Humans Hydrocortisone Hydrocortisone - therapeutic use Hypoxia Hypoxia - complications Hypoxia - drug therapy Intravenous administration Mechanical ventilation Medicin och hälsovetenskap Mortality Original Aritlce Pandemics Patients Quality of life Research Design Severe acute respiratory syndrome Special Statistical analysis Statistics Steroids Treatment Outcome Ventilation Ventilators
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