Can nutritional interventions modulate the activation of the NLRP3 inflammasome in chronic kidney disease?

[Display omitted] •Chronic kidney disease (CKD) is linked to chronic inflammation.•NLRP3 is thought to play a crucial role in underlying inflammatory responses.•Bioactive compounds can decrease the activation of the NLRP3.•Concept of “Food as Medicine” should be used in CKD. Inflammatory and innate...

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Veröffentlicht in:	Food research international 2020-10, Vol.136, p.109306-109306, Article 109306
Hauptverfasser:	Alvarenga, Livia, Cardozo, Ludmila F.M.F., Borges, Natália A., Lindholm, Bengt, Stenvinkel, Peter, Shiels, Paul G., Fouque, Denis, Mafra, Denise
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bioactive compound Caloric Restriction Chronic kidney disease Fatty Acids, Unsaturated - administration & dosage Humans Immunity, Innate Inflammasome Inflammasomes - physiology Inflammation Inflammation - physiopathology Life Sciences NLR Family, Pyrin Domain-Containing 3 Protein - physiology Nutrition Therapy - methods Oxidative stress Phytochemicals - administration & dosage Probiotics Renal Insufficiency, Chronic - diet therapy Renal Insufficiency, Chronic - physiopathology Renal Insufficiency, Chronic - prevention & control
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