GPR43 regulates marginal zone B‐cell responses to foreign and endogenous antigens

Marginal zone (MZ) B cells are innate‐like B cells that produce polyreactive antibodies with an affinity for microbial molecular patterns and carbohydrate ligands. MZ B cells have been shown to be important in mediating immunity to various bacteria including Streptococcus pneumoniae and are also imp...

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Veröffentlicht in:	Immunology and cell biology 2021-02, Vol.99 (2), p.234-243
Hauptverfasser:	Rohrbeck, Leona, Adori, Monika, Wang, Shan, He, Chenfei, Tibbitt, Christopher A, Chernyshev, Mark, Sirel, Madle, Ribacke, Ulf, Murrell, Ben, Bohlooly‐Y, Mohammad, Karlsson, Mikael CI, Karlsson Hedestam, Gunilla B, Coquet, Jonathan M
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigens Autoantibodies Cell surface Fatty acids Fiber GPR43 Immunoglobulin M Inflammation Intestinal microflora Intestine Lecithin Lymphocytes B marginal zone B cells Medicin och hälsovetenskap Microbiota mRNA Phosphatidylcholine polysaccharide vaccine Polysaccharides Short Communication short‐chain fatty acids Spleen Streptococcus infections Surface markers
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