Dual-adjuvant effect of pH-sensitive liposomes loaded with STING and TLR9 agonists regress tumor development by enhancing Th1 immune response

Nucleic acid-based pattern recognition receptor agonists are effective adjuvants and immunotherapeutic agents. Rather than single applications, ligand combinations could synergistically potentiate immune responses by elevating cytokine and chemokine production via triggering multiple signaling pathw...

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Veröffentlicht in:	JOURNAL OF CONTROLLED RELEASE 2020-12, Vol.328, p.587-595
Hauptverfasser:	Bayyurt Kocabas, Banu, Almacioglu, Kubra, Bulut, Esin Alpdundar, Gucluler, Gozde, Tincer, Gizem, Bayik, Defne, Gursel, Mayda, Gursel, Ihsan
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer immunotherapy cGAMP CpG ODN Immune-adjuvant synergy Medicin och hälsovetenskap pH-sensitive liposome
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