The case for simplifying and using absolute targets for viral hepatitis elimination goals
The 69th World Health Assembly endorsed the Global Health Sector Strategy for Viral Hepatitis, embracing a goal to eliminate hepatitis infection as a public health threat by 2030. This was followed by the World Health Organization's (WHO) global targets for the care and management of hepatitis...
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Veröffentlicht in: | Journal of Viral Hepatitis 2021-01, Vol.28 (1), p.12-19 |
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creator | Razavi, Homie Blach, Sarah Abaalkhail, Faisal Abbas, Zaigham Abdallah, Ayat Abu Raddad, Laith Jamal Ahmed, Aijaz Al‐Busafi, Said A Al‐hamoudi, Waleed Aljarallah, Badr Alswat, Khalid Asselah, Tarik Bessone, Fernando Block, Tim Bonino, Ferruccio Brunetto, Maurizia Rossana Buti, Maria Cabezas, Joaquín Calleja, Jose Luis Castro Batänjer, Erika Chen, Chien‐Jen Christensen, Peer Brehm Cisneros, Laura Cohen, Chari Conway, Brian Cooper, Curtis Craxi, Antonio Cupertino de Barros, Fernando Passos Dillon, John Duberg, Ann‐Sofi Dugan, Ellen Dunn, Rick El‐Sayed, Manal H Falconer, Karolin Fassio, Eduardo Flamm, Steven Fung, James García‐Samaniego, Javier Hamoudi, Waseem Hoepelman, I. M. Hsu, Yao‐Chun Hui, Yee Tak Jacobson, Ira Janjua, Naveed Jarcuska, Peter Kao, Jia‐Horng Kaymakoglu, Sabahattin Kim, Do Young Kottilil, Shyamasundaran Kugelmas, Marcelo Lacombe, Karine Lao, Wai‐Cheung Lee, Samual S Liakina, Valentina Liu, Shuang Malekzadeh, Reza Mathur, Poonam Mera, Jorge Muellhaupt, Beat Muljono, David Nahum, Mendez Sanchez Nawaz, Arif Negro, Francesco Oevrehus, Anne Osman, Alaa Oyunsuren, Tsendsuren Pan, Calvin Papatheodoridis, George Prithiviputh, Rittoo Qureshi, Huma Ramji, Alnoor Remak, William Robaeys, Geert Saab, Sammy Said, Sanaa Salamat, Amjad Sanai, Faisal Sebastiani, Giada Seguin‐Devaux, Carole Sharara, Ala Shouval, Daniel Sievert, William Simonova, Marieta Sohrabpour, Amir Ali Soza, Alejandro Steinfurth, Nancy Tanaka, Junko Thein, Hla‐Hla Tolmane, Ieva Toy, Mehlika Valantinas, Jonas Van de Vijver, David Vince, Adriana Wedemeyer, Heiner Xie, Qing Yesmembetov, Kakharman Yilmaz, Yusuf Yu, Ming‐Lung Yurdaydin, Cihan Zekry, Amany |
description | The 69th World Health Assembly endorsed the Global Health Sector Strategy for Viral Hepatitis, embracing a goal to eliminate hepatitis infection as a public health threat by 2030. This was followed by the World Health Organization's (WHO) global targets for the care and management of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. These announcements and targets were important in raising awareness and calling for action; however, tracking countries’ progress towards these elimination goals has provided insights to the limitations of these targets. The existing targets compare a country's progress relative to its 2015 values, penalizing countries who started their programmes prior to 2015, countries with a young population, or countries with a low prevalence. We recommend that (1) WHO simplify the hepatitis elimination targets, (2) change to absolute targets and (3) allow countries to achieve these disease targets with their own service coverage initiatives that will have the maximum impact. The recommended targets are as follows: reduce HCV new chronic cases to ≤5 per 100 000, reduce HBV prevalence among 1‐year‐olds to ≤0.1%, reduce HBV and HCV mortality to ≤5 per 100 000, and demonstrate HBV and HCV year‐to‐year decrease in new HCV‐ and HBV‐related HCC cases. The objective of our recommendations is not to lower expectations or diminish the hepatitis elimination standards, but to provide clearer targets that recognize the past and current elimination efforts by countries, help measure progress towards true elimination, and motivate other countries to follow suit. |
doi_str_mv | 10.1111/jvh.13412 |
format | Article |
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M. ; Hsu, Yao‐Chun ; Hui, Yee Tak ; Jacobson, Ira ; Janjua, Naveed ; Jarcuska, Peter ; Kao, Jia‐Horng ; Kaymakoglu, Sabahattin ; Kim, Do Young ; Kottilil, Shyamasundaran ; Kugelmas, Marcelo ; Lacombe, Karine ; Lao, Wai‐Cheung ; Lee, Samual S ; Liakina, Valentina ; Liu, Shuang ; Malekzadeh, Reza ; Mathur, Poonam ; Mera, Jorge ; Muellhaupt, Beat ; Muljono, David ; Nahum, Mendez Sanchez ; Nawaz, Arif ; Negro, Francesco ; Oevrehus, Anne ; Osman, Alaa ; Oyunsuren, Tsendsuren ; Pan, Calvin ; Papatheodoridis, George ; Prithiviputh, Rittoo ; Qureshi, Huma ; Ramji, Alnoor ; Remak, William ; Robaeys, Geert ; Saab, Sammy ; Said, Sanaa ; Salamat, Amjad ; Sanai, Faisal ; Sebastiani, Giada ; Seguin‐Devaux, Carole ; Sharara, Ala ; Shouval, Daniel ; Sievert, William ; Simonova, Marieta ; Sohrabpour, Amir Ali ; Soza, Alejandro ; Steinfurth, Nancy ; Tanaka, Junko ; Thein, Hla‐Hla ; Tolmane, Ieva ; Toy, Mehlika ; Valantinas, Jonas ; Van de Vijver, David ; Vince, Adriana ; Wedemeyer, Heiner ; Xie, Qing ; Yesmembetov, Kakharman ; Yilmaz, Yusuf ; Yu, Ming‐Lung ; Yurdaydin, Cihan ; Zekry, Amany</creator><creatorcontrib>Razavi, Homie ; Blach, Sarah ; Abaalkhail, Faisal ; Abbas, Zaigham ; Abdallah, Ayat ; Abu Raddad, Laith Jamal ; Ahmed, Aijaz ; Al‐Busafi, Said A ; Al‐hamoudi, Waleed ; Aljarallah, Badr ; Alswat, Khalid ; Asselah, Tarik ; Bessone, Fernando ; Block, Tim ; Bonino, Ferruccio ; Brunetto, Maurizia Rossana ; Buti, Maria ; Cabezas, Joaquín ; Calleja, Jose Luis ; Castro Batänjer, Erika ; Chen, Chien‐Jen ; Christensen, Peer Brehm ; Cisneros, Laura ; Cohen, Chari ; Conway, Brian ; Cooper, Curtis ; Craxi, Antonio ; Cupertino de Barros, Fernando Passos ; Dillon, John ; Duberg, Ann‐Sofi ; Dugan, Ellen ; Dunn, Rick ; El‐Sayed, Manal H ; Falconer, Karolin ; Fassio, Eduardo ; Flamm, Steven ; Fung, James ; García‐Samaniego, Javier ; Hamoudi, Waseem ; Hoepelman, I. M. ; Hsu, Yao‐Chun ; Hui, Yee Tak ; Jacobson, Ira ; Janjua, Naveed ; Jarcuska, Peter ; Kao, Jia‐Horng ; Kaymakoglu, Sabahattin ; Kim, Do Young ; Kottilil, Shyamasundaran ; Kugelmas, Marcelo ; Lacombe, Karine ; Lao, Wai‐Cheung ; Lee, Samual S ; Liakina, Valentina ; Liu, Shuang ; Malekzadeh, Reza ; Mathur, Poonam ; Mera, Jorge ; Muellhaupt, Beat ; Muljono, David ; Nahum, Mendez Sanchez ; Nawaz, Arif ; Negro, Francesco ; Oevrehus, Anne ; Osman, Alaa ; Oyunsuren, Tsendsuren ; Pan, Calvin ; Papatheodoridis, George ; Prithiviputh, Rittoo ; Qureshi, Huma ; Ramji, Alnoor ; Remak, William ; Robaeys, Geert ; Saab, Sammy ; Said, Sanaa ; Salamat, Amjad ; Sanai, Faisal ; Sebastiani, Giada ; Seguin‐Devaux, Carole ; Sharara, Ala ; Shouval, Daniel ; Sievert, William ; Simonova, Marieta ; Sohrabpour, Amir Ali ; Soza, Alejandro ; Steinfurth, Nancy ; Tanaka, Junko ; Thein, Hla‐Hla ; Tolmane, Ieva ; Toy, Mehlika ; Valantinas, Jonas ; Van de Vijver, David ; Vince, Adriana ; Wedemeyer, Heiner ; Xie, Qing ; Yesmembetov, Kakharman ; Yilmaz, Yusuf ; Yu, Ming‐Lung ; Yurdaydin, Cihan ; Zekry, Amany ; Polaris Observatory Collaborators</creatorcontrib><description>The 69th World Health Assembly endorsed the Global Health Sector Strategy for Viral Hepatitis, embracing a goal to eliminate hepatitis infection as a public health threat by 2030. This was followed by the World Health Organization's (WHO) global targets for the care and management of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. These announcements and targets were important in raising awareness and calling for action; however, tracking countries’ progress towards these elimination goals has provided insights to the limitations of these targets. The existing targets compare a country's progress relative to its 2015 values, penalizing countries who started their programmes prior to 2015, countries with a young population, or countries with a low prevalence. We recommend that (1) WHO simplify the hepatitis elimination targets, (2) change to absolute targets and (3) allow countries to achieve these disease targets with their own service coverage initiatives that will have the maximum impact. The recommended targets are as follows: reduce HCV new chronic cases to ≤5 per 100 000, reduce HBV prevalence among 1‐year‐olds to ≤0.1%, reduce HBV and HCV mortality to ≤5 per 100 000, and demonstrate HBV and HCV year‐to‐year decrease in new HCV‐ and HBV‐related HCC cases. The objective of our recommendations is not to lower expectations or diminish the hepatitis elimination standards, but to provide clearer targets that recognize the past and current elimination efforts by countries, help measure progress towards true elimination, and motivate other countries to follow suit.</description><identifier>ISSN: 1352-0504</identifier><identifier>ISSN: 1365-2893</identifier><identifier>EISSN: 1365-2893</identifier><identifier>DOI: 10.1111/jvh.13412</identifier><identifier>PMID: 32979881</identifier><language>eng</language><publisher>England: Wiley Subscription Services, Inc</publisher><subject>Hepatitis ; Hepatitis B ; Hepatitis C ; Life Sciences ; Public health</subject><ispartof>Journal of Viral Hepatitis, 2021-01, Vol.28 (1), p.12-19</ispartof><rights>2020 John Wiley & Sons Ltd</rights><rights>2020 John Wiley & Sons Ltd.</rights><rights>Copyright © 2021 John Wiley & Sons Ltd</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4972-63c4494057538bf9c53b5cd54c9558ad11c2cc129d2a911bb90aafdd6ff04ba43</citedby><orcidid>0000-0002-2658-6930 ; 0000-0002-9252-7576 ; 0000-0002-0845-6833 ; 0000-0002-2659-1801 ; 0000-0003-4135-1053</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fjvh.13412$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fjvh.13412$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,314,550,776,780,881,1411,4010,27900,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32979881$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.sorbonne-universite.fr/hal-03707538$$DView record in HAL$$Hfree_for_read</backlink><backlink>$$Uhttps://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-87514$$DView record from Swedish Publication Index$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:145089140$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Razavi, Homie</creatorcontrib><creatorcontrib>Blach, Sarah</creatorcontrib><creatorcontrib>Abaalkhail, Faisal</creatorcontrib><creatorcontrib>Abbas, Zaigham</creatorcontrib><creatorcontrib>Abdallah, Ayat</creatorcontrib><creatorcontrib>Abu Raddad, Laith Jamal</creatorcontrib><creatorcontrib>Ahmed, Aijaz</creatorcontrib><creatorcontrib>Al‐Busafi, Said A</creatorcontrib><creatorcontrib>Al‐hamoudi, Waleed</creatorcontrib><creatorcontrib>Aljarallah, Badr</creatorcontrib><creatorcontrib>Alswat, Khalid</creatorcontrib><creatorcontrib>Asselah, Tarik</creatorcontrib><creatorcontrib>Bessone, Fernando</creatorcontrib><creatorcontrib>Block, Tim</creatorcontrib><creatorcontrib>Bonino, Ferruccio</creatorcontrib><creatorcontrib>Brunetto, Maurizia Rossana</creatorcontrib><creatorcontrib>Buti, Maria</creatorcontrib><creatorcontrib>Cabezas, Joaquín</creatorcontrib><creatorcontrib>Calleja, Jose Luis</creatorcontrib><creatorcontrib>Castro Batänjer, Erika</creatorcontrib><creatorcontrib>Chen, Chien‐Jen</creatorcontrib><creatorcontrib>Christensen, Peer Brehm</creatorcontrib><creatorcontrib>Cisneros, Laura</creatorcontrib><creatorcontrib>Cohen, Chari</creatorcontrib><creatorcontrib>Conway, Brian</creatorcontrib><creatorcontrib>Cooper, Curtis</creatorcontrib><creatorcontrib>Craxi, Antonio</creatorcontrib><creatorcontrib>Cupertino de Barros, Fernando Passos</creatorcontrib><creatorcontrib>Dillon, John</creatorcontrib><creatorcontrib>Duberg, Ann‐Sofi</creatorcontrib><creatorcontrib>Dugan, Ellen</creatorcontrib><creatorcontrib>Dunn, Rick</creatorcontrib><creatorcontrib>El‐Sayed, Manal H</creatorcontrib><creatorcontrib>Falconer, Karolin</creatorcontrib><creatorcontrib>Fassio, Eduardo</creatorcontrib><creatorcontrib>Flamm, Steven</creatorcontrib><creatorcontrib>Fung, James</creatorcontrib><creatorcontrib>García‐Samaniego, Javier</creatorcontrib><creatorcontrib>Hamoudi, Waseem</creatorcontrib><creatorcontrib>Hoepelman, I. M.</creatorcontrib><creatorcontrib>Hsu, Yao‐Chun</creatorcontrib><creatorcontrib>Hui, Yee Tak</creatorcontrib><creatorcontrib>Jacobson, Ira</creatorcontrib><creatorcontrib>Janjua, Naveed</creatorcontrib><creatorcontrib>Jarcuska, Peter</creatorcontrib><creatorcontrib>Kao, Jia‐Horng</creatorcontrib><creatorcontrib>Kaymakoglu, Sabahattin</creatorcontrib><creatorcontrib>Kim, Do Young</creatorcontrib><creatorcontrib>Kottilil, Shyamasundaran</creatorcontrib><creatorcontrib>Kugelmas, Marcelo</creatorcontrib><creatorcontrib>Lacombe, Karine</creatorcontrib><creatorcontrib>Lao, Wai‐Cheung</creatorcontrib><creatorcontrib>Lee, Samual S</creatorcontrib><creatorcontrib>Liakina, Valentina</creatorcontrib><creatorcontrib>Liu, Shuang</creatorcontrib><creatorcontrib>Malekzadeh, Reza</creatorcontrib><creatorcontrib>Mathur, Poonam</creatorcontrib><creatorcontrib>Mera, Jorge</creatorcontrib><creatorcontrib>Muellhaupt, Beat</creatorcontrib><creatorcontrib>Muljono, David</creatorcontrib><creatorcontrib>Nahum, Mendez Sanchez</creatorcontrib><creatorcontrib>Nawaz, Arif</creatorcontrib><creatorcontrib>Negro, Francesco</creatorcontrib><creatorcontrib>Oevrehus, Anne</creatorcontrib><creatorcontrib>Osman, Alaa</creatorcontrib><creatorcontrib>Oyunsuren, Tsendsuren</creatorcontrib><creatorcontrib>Pan, Calvin</creatorcontrib><creatorcontrib>Papatheodoridis, George</creatorcontrib><creatorcontrib>Prithiviputh, Rittoo</creatorcontrib><creatorcontrib>Qureshi, Huma</creatorcontrib><creatorcontrib>Ramji, Alnoor</creatorcontrib><creatorcontrib>Remak, William</creatorcontrib><creatorcontrib>Robaeys, Geert</creatorcontrib><creatorcontrib>Saab, Sammy</creatorcontrib><creatorcontrib>Said, Sanaa</creatorcontrib><creatorcontrib>Salamat, Amjad</creatorcontrib><creatorcontrib>Sanai, Faisal</creatorcontrib><creatorcontrib>Sebastiani, Giada</creatorcontrib><creatorcontrib>Seguin‐Devaux, Carole</creatorcontrib><creatorcontrib>Sharara, Ala</creatorcontrib><creatorcontrib>Shouval, Daniel</creatorcontrib><creatorcontrib>Sievert, William</creatorcontrib><creatorcontrib>Simonova, Marieta</creatorcontrib><creatorcontrib>Sohrabpour, Amir Ali</creatorcontrib><creatorcontrib>Soza, Alejandro</creatorcontrib><creatorcontrib>Steinfurth, Nancy</creatorcontrib><creatorcontrib>Tanaka, Junko</creatorcontrib><creatorcontrib>Thein, Hla‐Hla</creatorcontrib><creatorcontrib>Tolmane, Ieva</creatorcontrib><creatorcontrib>Toy, Mehlika</creatorcontrib><creatorcontrib>Valantinas, Jonas</creatorcontrib><creatorcontrib>Van de Vijver, David</creatorcontrib><creatorcontrib>Vince, Adriana</creatorcontrib><creatorcontrib>Wedemeyer, Heiner</creatorcontrib><creatorcontrib>Xie, Qing</creatorcontrib><creatorcontrib>Yesmembetov, Kakharman</creatorcontrib><creatorcontrib>Yilmaz, Yusuf</creatorcontrib><creatorcontrib>Yu, Ming‐Lung</creatorcontrib><creatorcontrib>Yurdaydin, Cihan</creatorcontrib><creatorcontrib>Zekry, Amany</creatorcontrib><creatorcontrib>Polaris Observatory Collaborators</creatorcontrib><title>The case for simplifying and using absolute targets for viral hepatitis elimination goals</title><title>Journal of Viral Hepatitis</title><addtitle>J Viral Hepat</addtitle><description>The 69th World Health Assembly endorsed the Global Health Sector Strategy for Viral Hepatitis, embracing a goal to eliminate hepatitis infection as a public health threat by 2030. This was followed by the World Health Organization's (WHO) global targets for the care and management of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. These announcements and targets were important in raising awareness and calling for action; however, tracking countries’ progress towards these elimination goals has provided insights to the limitations of these targets. The existing targets compare a country's progress relative to its 2015 values, penalizing countries who started their programmes prior to 2015, countries with a young population, or countries with a low prevalence. We recommend that (1) WHO simplify the hepatitis elimination targets, (2) change to absolute targets and (3) allow countries to achieve these disease targets with their own service coverage initiatives that will have the maximum impact. The recommended targets are as follows: reduce HCV new chronic cases to ≤5 per 100 000, reduce HBV prevalence among 1‐year‐olds to ≤0.1%, reduce HBV and HCV mortality to ≤5 per 100 000, and demonstrate HBV and HCV year‐to‐year decrease in new HCV‐ and HBV‐related HCC cases. The objective of our recommendations is not to lower expectations or diminish the hepatitis elimination standards, but to provide clearer targets that recognize the past and current elimination efforts by countries, help measure progress towards true elimination, and motivate other countries to follow suit.</description><subject>Hepatitis</subject><subject>Hepatitis B</subject><subject>Hepatitis C</subject><subject>Life Sciences</subject><subject>Public health</subject><issn>1352-0504</issn><issn>1365-2893</issn><issn>1365-2893</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>D8T</sourceid><recordid>eNp1kUtr3DAUhUVpadK0i_6BIuimhTjR07aWQ_qYhoFu0kBXQpblGU1ly5HsCfPvK48nKQ1EIO7R5ePciw4A7zG6wOlcbnebC0wZJi_AKaY5z0gp6MtJc5IhjtgJeBPjFiFMCcevwQklohBliU_B75uNgVpFAxsfYLRt72yzt90aqq6GYzyoKno3DgYOKqzNEA_ozgbl4Mb0arCDjdA429ouPXwH1165-Ba8alIx7471DPz69vXmapmtfn7_cbVYZZqJgmQ51YwJhnjBaVk1QnNacV1zpgXnpaox1kRrTERNlMC4qgRSqqnrvGkQqxSjZyCbfeO96cdK9sG2KuylV1YeW3-SMpLlRUlo4s-f5b_Y24X0YZ3uKMuC48n-84xvlPuPXS5WcuohWqBp9x1O7KeZ7YO_G00cZGujNs6pzvgxSsJYnpeIFZPtxyfo1o-hSx-VqAIxQQQT_4br4GMMpnncACM5RS9T9PIQfWI_HB3HqjX1I_mQdQIuZ-DeOrN_3kle3y5ny7-MCrf4</recordid><startdate>202101</startdate><enddate>202101</enddate><creator>Razavi, Homie</creator><creator>Blach, Sarah</creator><creator>Abaalkhail, Faisal</creator><creator>Abbas, Zaigham</creator><creator>Abdallah, Ayat</creator><creator>Abu Raddad, Laith Jamal</creator><creator>Ahmed, Aijaz</creator><creator>Al‐Busafi, Said A</creator><creator>Al‐hamoudi, Waleed</creator><creator>Aljarallah, Badr</creator><creator>Alswat, Khalid</creator><creator>Asselah, Tarik</creator><creator>Bessone, Fernando</creator><creator>Block, Tim</creator><creator>Bonino, Ferruccio</creator><creator>Brunetto, Maurizia Rossana</creator><creator>Buti, Maria</creator><creator>Cabezas, Joaquín</creator><creator>Calleja, Jose Luis</creator><creator>Castro Batänjer, Erika</creator><creator>Chen, Chien‐Jen</creator><creator>Christensen, Peer Brehm</creator><creator>Cisneros, Laura</creator><creator>Cohen, Chari</creator><creator>Conway, Brian</creator><creator>Cooper, Curtis</creator><creator>Craxi, Antonio</creator><creator>Cupertino de Barros, Fernando Passos</creator><creator>Dillon, John</creator><creator>Duberg, Ann‐Sofi</creator><creator>Dugan, Ellen</creator><creator>Dunn, Rick</creator><creator>El‐Sayed, Manal H</creator><creator>Falconer, Karolin</creator><creator>Fassio, Eduardo</creator><creator>Flamm, Steven</creator><creator>Fung, James</creator><creator>García‐Samaniego, Javier</creator><creator>Hamoudi, Waseem</creator><creator>Hoepelman, I. 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M. ; Hsu, Yao‐Chun ; Hui, Yee Tak ; Jacobson, Ira ; Janjua, Naveed ; Jarcuska, Peter ; Kao, Jia‐Horng ; Kaymakoglu, Sabahattin ; Kim, Do Young ; Kottilil, Shyamasundaran ; Kugelmas, Marcelo ; Lacombe, Karine ; Lao, Wai‐Cheung ; Lee, Samual S ; Liakina, Valentina ; Liu, Shuang ; Malekzadeh, Reza ; Mathur, Poonam ; Mera, Jorge ; Muellhaupt, Beat ; Muljono, David ; Nahum, Mendez Sanchez ; Nawaz, Arif ; Negro, Francesco ; Oevrehus, Anne ; Osman, Alaa ; Oyunsuren, Tsendsuren ; Pan, Calvin ; Papatheodoridis, George ; Prithiviputh, Rittoo ; Qureshi, Huma ; Ramji, Alnoor ; Remak, William ; Robaeys, Geert ; Saab, Sammy ; Said, Sanaa ; Salamat, Amjad ; Sanai, Faisal ; Sebastiani, Giada ; Seguin‐Devaux, Carole ; Sharara, Ala ; Shouval, Daniel ; Sievert, William ; Simonova, Marieta ; Sohrabpour, Amir Ali ; Soza, Alejandro ; Steinfurth, Nancy ; Tanaka, Junko ; Thein, Hla‐Hla ; Tolmane, Ieva ; Toy, Mehlika ; Valantinas, Jonas ; Van de Vijver, David ; Vince, Adriana ; Wedemeyer, Heiner ; Xie, Qing ; Yesmembetov, Kakharman ; Yilmaz, Yusuf ; Yu, Ming‐Lung ; Yurdaydin, Cihan ; Zekry, Amany</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4972-63c4494057538bf9c53b5cd54c9558ad11c2cc129d2a911bb90aafdd6ff04ba43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Hepatitis</topic><topic>Hepatitis B</topic><topic>Hepatitis C</topic><topic>Life Sciences</topic><topic>Public health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Razavi, Homie</creatorcontrib><creatorcontrib>Blach, Sarah</creatorcontrib><creatorcontrib>Abaalkhail, Faisal</creatorcontrib><creatorcontrib>Abbas, Zaigham</creatorcontrib><creatorcontrib>Abdallah, Ayat</creatorcontrib><creatorcontrib>Abu Raddad, Laith Jamal</creatorcontrib><creatorcontrib>Ahmed, Aijaz</creatorcontrib><creatorcontrib>Al‐Busafi, Said A</creatorcontrib><creatorcontrib>Al‐hamoudi, Waleed</creatorcontrib><creatorcontrib>Aljarallah, Badr</creatorcontrib><creatorcontrib>Alswat, Khalid</creatorcontrib><creatorcontrib>Asselah, Tarik</creatorcontrib><creatorcontrib>Bessone, Fernando</creatorcontrib><creatorcontrib>Block, Tim</creatorcontrib><creatorcontrib>Bonino, Ferruccio</creatorcontrib><creatorcontrib>Brunetto, Maurizia Rossana</creatorcontrib><creatorcontrib>Buti, Maria</creatorcontrib><creatorcontrib>Cabezas, Joaquín</creatorcontrib><creatorcontrib>Calleja, Jose Luis</creatorcontrib><creatorcontrib>Castro Batänjer, Erika</creatorcontrib><creatorcontrib>Chen, Chien‐Jen</creatorcontrib><creatorcontrib>Christensen, Peer Brehm</creatorcontrib><creatorcontrib>Cisneros, Laura</creatorcontrib><creatorcontrib>Cohen, Chari</creatorcontrib><creatorcontrib>Conway, Brian</creatorcontrib><creatorcontrib>Cooper, Curtis</creatorcontrib><creatorcontrib>Craxi, Antonio</creatorcontrib><creatorcontrib>Cupertino de Barros, Fernando Passos</creatorcontrib><creatorcontrib>Dillon, John</creatorcontrib><creatorcontrib>Duberg, Ann‐Sofi</creatorcontrib><creatorcontrib>Dugan, Ellen</creatorcontrib><creatorcontrib>Dunn, Rick</creatorcontrib><creatorcontrib>El‐Sayed, Manal H</creatorcontrib><creatorcontrib>Falconer, Karolin</creatorcontrib><creatorcontrib>Fassio, Eduardo</creatorcontrib><creatorcontrib>Flamm, Steven</creatorcontrib><creatorcontrib>Fung, James</creatorcontrib><creatorcontrib>García‐Samaniego, Javier</creatorcontrib><creatorcontrib>Hamoudi, Waseem</creatorcontrib><creatorcontrib>Hoepelman, I. 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M.</au><au>Hsu, Yao‐Chun</au><au>Hui, Yee Tak</au><au>Jacobson, Ira</au><au>Janjua, Naveed</au><au>Jarcuska, Peter</au><au>Kao, Jia‐Horng</au><au>Kaymakoglu, Sabahattin</au><au>Kim, Do Young</au><au>Kottilil, Shyamasundaran</au><au>Kugelmas, Marcelo</au><au>Lacombe, Karine</au><au>Lao, Wai‐Cheung</au><au>Lee, Samual S</au><au>Liakina, Valentina</au><au>Liu, Shuang</au><au>Malekzadeh, Reza</au><au>Mathur, Poonam</au><au>Mera, Jorge</au><au>Muellhaupt, Beat</au><au>Muljono, David</au><au>Nahum, Mendez Sanchez</au><au>Nawaz, Arif</au><au>Negro, Francesco</au><au>Oevrehus, Anne</au><au>Osman, Alaa</au><au>Oyunsuren, Tsendsuren</au><au>Pan, Calvin</au><au>Papatheodoridis, George</au><au>Prithiviputh, Rittoo</au><au>Qureshi, Huma</au><au>Ramji, Alnoor</au><au>Remak, William</au><au>Robaeys, Geert</au><au>Saab, Sammy</au><au>Said, Sanaa</au><au>Salamat, Amjad</au><au>Sanai, Faisal</au><au>Sebastiani, Giada</au><au>Seguin‐Devaux, Carole</au><au>Sharara, Ala</au><au>Shouval, Daniel</au><au>Sievert, William</au><au>Simonova, Marieta</au><au>Sohrabpour, Amir Ali</au><au>Soza, Alejandro</au><au>Steinfurth, Nancy</au><au>Tanaka, Junko</au><au>Thein, Hla‐Hla</au><au>Tolmane, Ieva</au><au>Toy, Mehlika</au><au>Valantinas, Jonas</au><au>Van de Vijver, David</au><au>Vince, Adriana</au><au>Wedemeyer, Heiner</au><au>Xie, Qing</au><au>Yesmembetov, Kakharman</au><au>Yilmaz, Yusuf</au><au>Yu, Ming‐Lung</au><au>Yurdaydin, Cihan</au><au>Zekry, Amany</au><aucorp>Polaris Observatory Collaborators</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The case for simplifying and using absolute targets for viral hepatitis elimination goals</atitle><jtitle>Journal of Viral Hepatitis</jtitle><addtitle>J Viral Hepat</addtitle><date>2021-01</date><risdate>2021</risdate><volume>28</volume><issue>1</issue><spage>12</spage><epage>19</epage><pages>12-19</pages><issn>1352-0504</issn><issn>1365-2893</issn><eissn>1365-2893</eissn><abstract>The 69th World Health Assembly endorsed the Global Health Sector Strategy for Viral Hepatitis, embracing a goal to eliminate hepatitis infection as a public health threat by 2030. This was followed by the World Health Organization's (WHO) global targets for the care and management of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. These announcements and targets were important in raising awareness and calling for action; however, tracking countries’ progress towards these elimination goals has provided insights to the limitations of these targets. The existing targets compare a country's progress relative to its 2015 values, penalizing countries who started their programmes prior to 2015, countries with a young population, or countries with a low prevalence. We recommend that (1) WHO simplify the hepatitis elimination targets, (2) change to absolute targets and (3) allow countries to achieve these disease targets with their own service coverage initiatives that will have the maximum impact. The recommended targets are as follows: reduce HCV new chronic cases to ≤5 per 100 000, reduce HBV prevalence among 1‐year‐olds to ≤0.1%, reduce HBV and HCV mortality to ≤5 per 100 000, and demonstrate HBV and HCV year‐to‐year decrease in new HCV‐ and HBV‐related HCC cases. The objective of our recommendations is not to lower expectations or diminish the hepatitis elimination standards, but to provide clearer targets that recognize the past and current elimination efforts by countries, help measure progress towards true elimination, and motivate other countries to follow suit.</abstract><cop>England</cop><pub>Wiley Subscription Services, Inc</pub><pmid>32979881</pmid><doi>10.1111/jvh.13412</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-2658-6930</orcidid><orcidid>https://orcid.org/0000-0002-9252-7576</orcidid><orcidid>https://orcid.org/0000-0002-0845-6833</orcidid><orcidid>https://orcid.org/0000-0002-2659-1801</orcidid><orcidid>https://orcid.org/0000-0003-4135-1053</orcidid><oa>free_for_read</oa></addata></record> |
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source | Wiley Online Library Journals Frontfile Complete; SWEPUB Freely available online |
subjects | Hepatitis Hepatitis B Hepatitis C Life Sciences Public health |
title | The case for simplifying and using absolute targets for viral hepatitis elimination goals |
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