Synthesis and Autoradiography of Novel F‑18 Labeled Reversible Radioligands for Detection of Monoamine Oxidase B

Monoamine oxidase B (MAO-B) is an important enzyme regulating the levels of monoaminergic neurotransmitters. Selective MAO-B inhibitors have been labeled with carbon-11 or fluorine-18 to visualize the localization of MAO-B in vivo by positron emission tomography (PET) and thereby have been useful fo...

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Veröffentlicht in:	ACS chemical neuroscience 2020-12, Vol.11 (24), p.4398-4404
Hauptverfasser:	Nag, Sangram, Jia, Zhisheng, Svedberg, Marie, Jackson, Alex, Ahmad, Rabia, Luthra, Sajinder, Varnäs, Katarina, Farde, Lars, Halldin, Christer
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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