Assessment of Ki67 in Breast Cancer: Updated Recommendations From the International Ki67 in Breast Cancer Working Group

Abstract Ki67 immunohistochemistry (IHC), commonly used as a proliferation marker in breast cancer, has limited value for treatment decisions due to questionable analytical validity. The International Ki67 in Breast Cancer Working Group (IKWG) consensus meeting, held in October 2019, assessed the cu...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 2021-07, Vol.113 (7), p.808-819
Hauptverfasser:	Nielsen, Torsten O, Leung, Samuel C. Y, Rimm, David L, Dodson, Andrew, Acs, Balazs, Badve, Sunil, Denkert, Carsten, Ellis, Matthew J, Fineberg, Susan, Flowers, Margaret, Kreipe, Hans H, Laenkholm, Anne-Vibeke, Pan, Hongchao, Penault-Llorca, Frédérique M, Polley, Mei-Yin, Salgado, Roberto, Smith, Ian E, Sugie, Tomoharu, Bartlett, John M. S, McShane, Lisa M, Dowsett, Mitch, Hayes, Daniel F
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor Breast cancer Breast Neoplasms - drug therapy Cancer Chemotherapy Commentaries Control programs Decision analysis ErbB-2 protein Estrogen receptors Estrogens Female Humans Immunohistochemistry Ki-67 Antigen Life Sciences Mathematical analysis Patients Prognosis Quality assurance Quality control Receptor, ErbB-2 Receptors Receptors, Estrogen Validity Working groups
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