HLA–B08 Identified as the Most Prominently Associated Major Histocompatibility Complex Locus for Anti–Carbamylated Protein Antibody–Positive/Anti–Cyclic Citrullinated Peptide–Negative Rheumatoid Arthritis

Objective Previously, only the HLA–DRB1 alleles have been assessed in rheumatoid arthritis (RA). The aim of the present study was to identify the key major histocompatibility complex (MHC) susceptibility factors showing a significant association with anti–carbamylated protein antibody–positive (anti...

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Veröffentlicht in:	Arthritis & rheumatology (Hoboken, N.J.) N.J.), 2021-06, Vol.73 (6), p.963-969
Hauptverfasser:	Regueiro, Cristina, Casares‐Marfil, Desire, Lundberg, Karin, Knevel, Rachel, Acosta‐Herrera, Marialbert, Rodriguez‐Rodriguez, Luis, Lopez‐Mejias, Raquel, Perez‐Pampin, Eva, Triguero‐Martinez, Ana, Nuño, Laura, Ferraz‐Amaro, Ivan, Rodriguez‐Carrio, Javier, Lopez‐Pedrera, Rosario, Robustillo‐Villarino, Montse, Castañeda, Santos, Remuzgo‐Martinez, Sara, Alperi, Mercedes, Alegre‐Sancho, Juan J., Balsa, Alejandro, Gonzalez‐Alvaro, Isidoro, Mera, Antonio, Fernandez‐Gutierrez, Benjamin, Gonzalez‐Gay, Miguel A., Trouw, Leendert A., Grönwall, Caroline, Padyukov, Leonid, Martin, Javier, Gonzalez, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Amino acids Antibodies Arthritis Autoantibodies Citrulline Drb1 protein Genotypes Genotyping Histocompatibility antigen HLA Linkage disequilibrium Loci Major histocompatibility complex Medicin och hälsovetenskap Peptides Population control Proteins Rheumatoid arthritis Susceptibility Variance analysis
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