Genetic architecture of schizophrenia: a review of major advancements

Schizophrenia is a severe psychiatric disorder with high heritability. Consortia efforts and technological advancements have led to a substantial increase in knowledge of the genetic architecture of schizophrenia over the past decade. In this article, we provide an overview of the current understand...

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Veröffentlicht in:	Psychological medicine 2021-10, Vol.51 (13), p.2168-2177
Hauptverfasser:	Legge, Sophie E., Santoro, Marcos L., Periyasamy, Sathish, Okewole, Adeniran, Arsalan, Arsalan, Kowalec, Kaarina
Format:	Artikel
Sprache:	eng
Schlagworte:	Biology Collaboration Consortia DNA Copy Number Variations - genetics Gene mapping Genes Genetic diversity Genetic Loci - genetics Genome-wide association studies Genome-Wide Association Study - trends Genomes Genomics Heritability Histone-Lysine N-Methyltransferase - genetics Humans International collaboration Invited Review Mapping Mental disorders Mortality Polymorphism, Single Nucleotide Population Psychiatric genetics Racial Groups - genetics Racial Groups - statistics & numerical data Schizophrenia Schizophrenia - genetics Schizophrenia - mortality Substance abuse treatment Variants Working groups
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