Non‐Animal Strategies for Toxicity Assessment of Nanoscale Materials: Role of Adverse Outcome Pathways in the Selection of Endpoints

Faster, cheaper, sensitive, and mechanisms‐based animal alternatives are needed to address the safety assessment needs of the growing number of nanomaterials (NM) and their sophisticated property variants. Specifically, strategies that help identify and prioritize alternative schemes involving indiv...

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Veröffentlicht in:	Small (Weinheim an der Bergstrasse, Germany) Germany), 2021-04, Vol.17 (15), p.e2007628-n/a
Hauptverfasser:	Halappanavar, Sabina, Nymark, Penny, Krug, Harald F., Clift, Martin J. D., Rothen‐Rutishauser, Barbara, Vogel, Ulla
Format:	Artikel
Sprache:	eng
Schlagworte:	Assaying Biocompatibility Fibrosis in vitro toxicity In vivo methods and tests Literature reviews lung fibrosis Lungs Nanomaterials nanoparticles Nanotechnology nanotoxicity Respiration risk assessment Toxicity testing
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