Can the biomolecular corona induce an allergic reaction?-A proof-of-concept study

Ferumoxytol nanoparticles are being used clinically for the treatment of anemia and molecular imaging in patients. It is well documented that while most patients tolerate ferumoxytol well, a small percentage of patients (i.e., 0.01%) develop severe allergic reactions. The purpose of our proof-of-con...

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Veröffentlicht in:	Biointerphases 2021-01, Vol.16 (1), p.011008-011008
Hauptverfasser:	Muehe, Anne, Nejadnik, Hossein, Muehe, Henrik, Rosenberg, Jarrett, Gharibi, Hassan, Saei, Amir Ata, Lyu, Shu-Chen, Nadeau, Kari C, Mahmoudi, Morteza, Daldrup-Link, Heike E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Basophils - metabolism Female Ferrosoferric Oxide - administration & dosage Humans Hypersensitivity - immunology Immunity Immunoglobulin E - metabolism Immunologic Memory Male Proof of Concept Study Protein Corona - chemistry T-Lymphocytes - immunology Young Adult
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