Virological and immunological features of SARS-CoV-2-infected children who develop neutralizing antibodies

As the global COVID-19 pandemic progresses, it is paramount to gain knowledge on adaptive immunity to SARS-CoV-2 in children to define immune correlates of protection upon immunization or infection. We analyzed anti-SARS-CoV-2 antibodies and their neutralizing activity (PRNT) in 66 COVID-19-infected...

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Veröffentlicht in:	Cell reports (Cambridge) 2021-03, Vol.34 (11), p.108852-108852, Article 108852
Hauptverfasser:	Cotugno, Nicola, Ruggiero, Alessandra, Bonfante, Francesco, Petrara, Maria Raffaella, Zicari, Sonia, Pascucci, Giuseppe Rubens, Zangari, Paola, De Ioris, Maria Antonietta, Santilli, Veronica, Manno, E.C., Amodio, Donato, Bortolami, Alessio, Pagliari, Matteo, Concato, Carlo, Linardos, Giulia, Campana, Andrea, Donà, Daniele, Giaquinto, Carlo, Bernardi, Stefania, Romani, Lorenza, Pansa, Paola, Chiurchiú, Sara, Finocchi, Andrea, Cancrini, Caterina, Lancella, Laura, Cursi, Laura, De Luca, Maia, Cutrera, Renato, Sessa, Libera, Morrocchi, Elena, Medri, Chiara, Putignani, Lorenza, Calò Carducci, F.I., D’Argenio, Patrizia, Ciofi degli Atti, Marta, D’Amore, Carmen, Piccioni, Livia, Di Giuseppe, Martina, Jenkner, Alessandro, Giancotta, Carmela, Krzysztofiak, Andrzej, Brodin, Petter, Rossi, Paolo, De Rossi, Anita, Palma, Paolo
Format:	Artikel
Sprache:	eng
Schlagworte:	Ab-mediated neutralization activity Adaptive Immunity - immunology anti-SARS-CoV-2 antibodies Antibodies, Neutralizing - immunology Antibodies, Viral - immunology antigen-specific B cells antigen-specific CD4 T cells B-Lymphocytes - immunology CD4-Positive T-Lymphocytes - immunology Child COVID-19 COVID-19 - immunology COVID-19 - virology Humans Immunity, Humoral - immunology pediatric COVID-19 Proteome - immunology proteomic profiling SARS-CoV-2 SARS-CoV-2 - immunology Signal Transduction - immunology Viral Load - immunology
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