IP6K2 predicts favorable clinical outcome of primary breast cancer

The inositol hexakisphosphate kinase ( ) 1 and 2 genes are localized at 3p21.31, a highly altered gene-dense chromosomal region in cancer. The IP6Ks convert IP6 to IP7, which inhibits activation of the tumor-promoting PI3K/Akt/mTOR signaling pathway. IP6K2 has been suggested to be involved in p53-in...

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Veröffentlicht in:	Molecular and clinical oncology 2021-05, Vol.14 (5), p.94-94, Article 94
Hauptverfasser:	Sandström, Josefine, Balian, Alien, Lockowandt, Rebecca, Fornander, Tommy, Nordenskjöld, Bo, Lindström, Linda, Pérez-Tenorio, Gizeh, Stål, Olle
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Apoptosis Breast cancer Cancer Cancer patients Care and treatment Clinical outcomes Ethnicity Gene expression Genes Genetic aspects Genomics Inositol Kinases Medical prognosis Medical research Medicine, Experimental Oncology Patient outcomes Patients Prognosis Protein expression Proteins Software Tumor proteins Tumors
Online-Zugang:	Volltext
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