Mesothelin-specific CAR T cells target ovarian cancer

New therapeutic options for patients with ovarian cancer are urgently needed. Therefore, we evaluated the efficacy of two second-generation mesothelin (MSLN)-directed CAR T cells in orthotopic mouse models of ovarian cancer. Treatment with CAR T cells expressing an MSLN CAR construct including the C...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2021-06, Vol.81 (11), p.3022-3035
Hauptverfasser:	Schoutrop, Esther, El-Serafi, Ibrahim, Poiret, Thomas, Zhao, Ying, Gultekin, Okan, He, Rui, Moyano-Galceran, Lidia, Carlson, Joseph W, Lehti, Kaisa, Hassan, Moustapha, Magalhaes, Isabelle, Mattsson, Jonas
Format:	Artikel
Sprache:	eng
Schlagworte:	Medicin och hälsovetenskap
Online-Zugang:	Volltext
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