Identification of undiagnosed dementia cases using a web‐based pre‐screening tool: The MOPEAD project
Introduction Innovative patient engagement models are required to identify people with prodromal and mild Alzheimer's disease who are “hidden” in their communities and not normally found in a memory clinic setting. Methods A marketing campaign and a web‐based pre‐screening tool were used to ide...
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| Veröffentlicht in: | Alzheimer's & dementia 2021-08, Vol.17 (8), p.1307-1316 |
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| container_title | Alzheimer's & dementia |
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| creator | Rodrigo, Adrián Trigueros, Paloma Jamilis, Laura Alegret, Montserrat Rodríguez, Octavio Tárraga, Lluís González‐Pérez, Antonio Kramberger, Milica Winblad, Bengt Visser, Pieter Jelle Jessen, Frank Campo, Laura Boada, Mercè |
| description | Introduction
Innovative patient engagement models are required to identify people with prodromal and mild Alzheimer's disease who are “hidden” in their communities and not normally found in a memory clinic setting.
Methods
A marketing campaign and a web‐based pre‐screening tool were used to identify individuals at risk of dementia in five European countries. Harmonized clinical evaluation of these patients was performed in participating memory clinics within the MOPEAD project.
Results
A total of 1487 individuals completed the pre‐screening, with 547 of them found to be at risk of dementia (36.8%). Among the subset of 91 patients with a positive pre‐screening result that underwent full clinical evaluation, 49 (53.8%) were diagnosed with either mild cognitive impairment or Alzheimer's disease.
Conclusion
This novel web‐based pre‐screening tool showed to be a valid strategy to identify undiagnosed people with cognitive impairment. |
| doi_str_mv | 10.1002/alz.12297 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_swepu</sourceid><recordid>TN_cdi_swepub_primary_oai_swepub_ki_se_462745</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2514604163</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4537-b1bd87a35f2b6d0bd43a1ee9be0cf823aed2c442ed876006c92de0091ddee4e13</originalsourceid><addsrcrecordid>eNp1kc1O3DAUha0KVOjQRV8AeUkXAf_FSbqoNKIUkAbBgm66sRz7ZjBk4iFOOoIVj9Bn5ElwyDAqi6585PP53GsdhL5QckgJYUe6fjykjBXZB7RL05QlKcuKrY2WZAd9CuGWEEFymn5EO5znkqRFsYvcuYWmc5UzunO-wb7CfWOdnjc-gMUWFoOtsdEBAu6Da-ZY4xWUz09_Sz0gyxaiDqYFaAa3877-hq9vAF9cXp1Mf0TA34Lp9tB2pesAn9fnBP36eXJ9fJbMLk_Pj6ezxIiUZ0lJS5tnmqcVK6UlpRVcU4CiBGKqnHENlhkhGERKEiJNwSwQUlBrAQRQPkHJmBtWsOxLtWzdQrcPymun1ld3UYESkmVx5AR9H_noLMCa-N9W1--evXcad6Pm_o_Kh325jAEH64DW3_cQOrVwwUBd6wZ8HxRLqZBEUMkj-nVETetDaKHajKFEDVWqWKV6rTKy-__utSHfuovA0QisXA0P_09S09nvMfIFvtatbw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2514604163</pqid></control><display><type>article</type><title>Identification of undiagnosed dementia cases using a web‐based pre‐screening tool: The MOPEAD project</title><source>Wiley Online Library - AutoHoldings Journals</source><source>SWEPUB Freely available online</source><creator>Rodrigo, Adrián ; Trigueros, Paloma ; Jamilis, Laura ; Alegret, Montserrat ; Rodríguez, Octavio ; Tárraga, Lluís ; González‐Pérez, Antonio ; Kramberger, Milica ; Winblad, Bengt ; Visser, Pieter Jelle ; Jessen, Frank ; Campo, Laura ; Boada, Mercè</creator><creatorcontrib>Rodrigo, Adrián ; Trigueros, Paloma ; Jamilis, Laura ; Alegret, Montserrat ; Rodríguez, Octavio ; Tárraga, Lluís ; González‐Pérez, Antonio ; Kramberger, Milica ; Winblad, Bengt ; Visser, Pieter Jelle ; Jessen, Frank ; Campo, Laura ; Boada, Mercè ; MOPEAD consortium ; the MOPEAD consortium</creatorcontrib><description>Introduction
Innovative patient engagement models are required to identify people with prodromal and mild Alzheimer's disease who are “hidden” in their communities and not normally found in a memory clinic setting.
Methods
A marketing campaign and a web‐based pre‐screening tool were used to identify individuals at risk of dementia in five European countries. Harmonized clinical evaluation of these patients was performed in participating memory clinics within the MOPEAD project.
Results
A total of 1487 individuals completed the pre‐screening, with 547 of them found to be at risk of dementia (36.8%). Among the subset of 91 patients with a positive pre‐screening result that underwent full clinical evaluation, 49 (53.8%) were diagnosed with either mild cognitive impairment or Alzheimer's disease.
Conclusion
This novel web‐based pre‐screening tool showed to be a valid strategy to identify undiagnosed people with cognitive impairment.</description><identifier>ISSN: 1552-5260</identifier><identifier>EISSN: 1552-5279</identifier><identifier>DOI: 10.1002/alz.12297</identifier><identifier>PMID: 33860599</identifier><language>eng</language><publisher>United States: John Wiley and Sons Inc</publisher><subject>Alzheimer's disease ; diagnostic gap ; early diagnosis ; patient engagement ; population‐based screening</subject><ispartof>Alzheimer's & dementia, 2021-08, Vol.17 (8), p.1307-1316</ispartof><rights>2021 The Authors. published by Wiley Periodicals LLC on behalf of Alzheimer's Association</rights><rights>2021 the Alzheimer's Association.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4537-b1bd87a35f2b6d0bd43a1ee9be0cf823aed2c442ed876006c92de0091ddee4e13</citedby><cites>FETCH-LOGICAL-c4537-b1bd87a35f2b6d0bd43a1ee9be0cf823aed2c442ed876006c92de0091ddee4e13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Falz.12297$$EPDF$$P50$$Gwiley$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Falz.12297$$EHTML$$P50$$Gwiley$$Hfree_for_read</linktohtml><link.rule.ids>230,314,550,776,780,881,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33860599$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:146552907$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Rodrigo, Adrián</creatorcontrib><creatorcontrib>Trigueros, Paloma</creatorcontrib><creatorcontrib>Jamilis, Laura</creatorcontrib><creatorcontrib>Alegret, Montserrat</creatorcontrib><creatorcontrib>Rodríguez, Octavio</creatorcontrib><creatorcontrib>Tárraga, Lluís</creatorcontrib><creatorcontrib>González‐Pérez, Antonio</creatorcontrib><creatorcontrib>Kramberger, Milica</creatorcontrib><creatorcontrib>Winblad, Bengt</creatorcontrib><creatorcontrib>Visser, Pieter Jelle</creatorcontrib><creatorcontrib>Jessen, Frank</creatorcontrib><creatorcontrib>Campo, Laura</creatorcontrib><creatorcontrib>Boada, Mercè</creatorcontrib><creatorcontrib>MOPEAD consortium</creatorcontrib><creatorcontrib>the MOPEAD consortium</creatorcontrib><title>Identification of undiagnosed dementia cases using a web‐based pre‐screening tool: The MOPEAD project</title><title>Alzheimer's & dementia</title><addtitle>Alzheimers Dement</addtitle><description>Introduction
Innovative patient engagement models are required to identify people with prodromal and mild Alzheimer's disease who are “hidden” in their communities and not normally found in a memory clinic setting.
Methods
A marketing campaign and a web‐based pre‐screening tool were used to identify individuals at risk of dementia in five European countries. Harmonized clinical evaluation of these patients was performed in participating memory clinics within the MOPEAD project.
Results
A total of 1487 individuals completed the pre‐screening, with 547 of them found to be at risk of dementia (36.8%). Among the subset of 91 patients with a positive pre‐screening result that underwent full clinical evaluation, 49 (53.8%) were diagnosed with either mild cognitive impairment or Alzheimer's disease.
Conclusion
This novel web‐based pre‐screening tool showed to be a valid strategy to identify undiagnosed people with cognitive impairment.</description><subject>Alzheimer's disease</subject><subject>diagnostic gap</subject><subject>early diagnosis</subject><subject>patient engagement</subject><subject>population‐based screening</subject><issn>1552-5260</issn><issn>1552-5279</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>D8T</sourceid><recordid>eNp1kc1O3DAUha0KVOjQRV8AeUkXAf_FSbqoNKIUkAbBgm66sRz7ZjBk4iFOOoIVj9Bn5ElwyDAqi6585PP53GsdhL5QckgJYUe6fjykjBXZB7RL05QlKcuKrY2WZAd9CuGWEEFymn5EO5znkqRFsYvcuYWmc5UzunO-wb7CfWOdnjc-gMUWFoOtsdEBAu6Da-ZY4xWUz09_Sz0gyxaiDqYFaAa3877-hq9vAF9cXp1Mf0TA34Lp9tB2pesAn9fnBP36eXJ9fJbMLk_Pj6ezxIiUZ0lJS5tnmqcVK6UlpRVcU4CiBGKqnHENlhkhGERKEiJNwSwQUlBrAQRQPkHJmBtWsOxLtWzdQrcPymun1ld3UYESkmVx5AR9H_noLMCa-N9W1--evXcad6Pm_o_Kh325jAEH64DW3_cQOrVwwUBd6wZ8HxRLqZBEUMkj-nVETetDaKHajKFEDVWqWKV6rTKy-__utSHfuovA0QisXA0P_09S09nvMfIFvtatbw</recordid><startdate>202108</startdate><enddate>202108</enddate><creator>Rodrigo, Adrián</creator><creator>Trigueros, Paloma</creator><creator>Jamilis, Laura</creator><creator>Alegret, Montserrat</creator><creator>Rodríguez, Octavio</creator><creator>Tárraga, Lluís</creator><creator>González‐Pérez, Antonio</creator><creator>Kramberger, Milica</creator><creator>Winblad, Bengt</creator><creator>Visser, Pieter Jelle</creator><creator>Jessen, Frank</creator><creator>Campo, Laura</creator><creator>Boada, Mercè</creator><general>John Wiley and Sons Inc</general><scope>24P</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><scope>ADTPV</scope><scope>AOWAS</scope><scope>D8T</scope><scope>ZZAVC</scope></search><sort><creationdate>202108</creationdate><title>Identification of undiagnosed dementia cases using a web‐based pre‐screening tool: The MOPEAD project</title><author>Rodrigo, Adrián ; Trigueros, Paloma ; Jamilis, Laura ; Alegret, Montserrat ; Rodríguez, Octavio ; Tárraga, Lluís ; González‐Pérez, Antonio ; Kramberger, Milica ; Winblad, Bengt ; Visser, Pieter Jelle ; Jessen, Frank ; Campo, Laura ; Boada, Mercè</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4537-b1bd87a35f2b6d0bd43a1ee9be0cf823aed2c442ed876006c92de0091ddee4e13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Alzheimer's disease</topic><topic>diagnostic gap</topic><topic>early diagnosis</topic><topic>patient engagement</topic><topic>population‐based screening</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rodrigo, Adrián</creatorcontrib><creatorcontrib>Trigueros, Paloma</creatorcontrib><creatorcontrib>Jamilis, Laura</creatorcontrib><creatorcontrib>Alegret, Montserrat</creatorcontrib><creatorcontrib>Rodríguez, Octavio</creatorcontrib><creatorcontrib>Tárraga, Lluís</creatorcontrib><creatorcontrib>González‐Pérez, Antonio</creatorcontrib><creatorcontrib>Kramberger, Milica</creatorcontrib><creatorcontrib>Winblad, Bengt</creatorcontrib><creatorcontrib>Visser, Pieter Jelle</creatorcontrib><creatorcontrib>Jessen, Frank</creatorcontrib><creatorcontrib>Campo, Laura</creatorcontrib><creatorcontrib>Boada, Mercè</creatorcontrib><creatorcontrib>MOPEAD consortium</creatorcontrib><creatorcontrib>the MOPEAD consortium</creatorcontrib><collection>Wiley Online Library Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>SwePub</collection><collection>SwePub Articles</collection><collection>SWEPUB Freely available online</collection><collection>SwePub Articles full text</collection><jtitle>Alzheimer's & dementia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rodrigo, Adrián</au><au>Trigueros, Paloma</au><au>Jamilis, Laura</au><au>Alegret, Montserrat</au><au>Rodríguez, Octavio</au><au>Tárraga, Lluís</au><au>González‐Pérez, Antonio</au><au>Kramberger, Milica</au><au>Winblad, Bengt</au><au>Visser, Pieter Jelle</au><au>Jessen, Frank</au><au>Campo, Laura</au><au>Boada, Mercè</au><aucorp>MOPEAD consortium</aucorp><aucorp>the MOPEAD consortium</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Identification of undiagnosed dementia cases using a web‐based pre‐screening tool: The MOPEAD project</atitle><jtitle>Alzheimer's & dementia</jtitle><addtitle>Alzheimers Dement</addtitle><date>2021-08</date><risdate>2021</risdate><volume>17</volume><issue>8</issue><spage>1307</spage><epage>1316</epage><pages>1307-1316</pages><issn>1552-5260</issn><eissn>1552-5279</eissn><abstract>Introduction
Innovative patient engagement models are required to identify people with prodromal and mild Alzheimer's disease who are “hidden” in their communities and not normally found in a memory clinic setting.
Methods
A marketing campaign and a web‐based pre‐screening tool were used to identify individuals at risk of dementia in five European countries. Harmonized clinical evaluation of these patients was performed in participating memory clinics within the MOPEAD project.
Results
A total of 1487 individuals completed the pre‐screening, with 547 of them found to be at risk of dementia (36.8%). Among the subset of 91 patients with a positive pre‐screening result that underwent full clinical evaluation, 49 (53.8%) were diagnosed with either mild cognitive impairment or Alzheimer's disease.
Conclusion
This novel web‐based pre‐screening tool showed to be a valid strategy to identify undiagnosed people with cognitive impairment.</abstract><cop>United States</cop><pub>John Wiley and Sons Inc</pub><pmid>33860599</pmid><doi>10.1002/alz.12297</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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| source | Wiley Online Library - AutoHoldings Journals; SWEPUB Freely available online |
| subjects | Alzheimer's disease diagnostic gap early diagnosis patient engagement population‐based screening |
| title | Identification of undiagnosed dementia cases using a web‐based pre‐screening tool: The MOPEAD project |
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