Lymph node metastases in breast cancer: Investigating associations with tumor characteristics, molecular subtypes and polygenic risk score using a continuous growth model

We investigate the association between rate of breast cancer lymph node spread and grade, estrogen receptor (ER) status, progesteron receptor status, decision tree derived PAM50 molecular subtype and a polygenic risk score (PRS), using data on 10 950 women included from two different data sources. L...

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Veröffentlicht in:	International journal of cancer 2021-09, Vol.149 (6), p.1348-1357
Hauptverfasser:	Isheden, Gabriel, Grassmann, Felix, Czene, Kamila, Humphreys, Keith
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Cancer continuous growth model ErbB-2 protein Estrogen receptors Growth models lymph node metastases Lymph nodes Lymphatic system Medical research Medicin och hälsovetenskap Metastases molecular subtype Polygenic inheritance polygenic risk score Tumors
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