Microdissected Pyramidal Cell Proteomics of Alzheimer Brain Reveals Alterations in Creatine Kinase B-Type, 14-3-3-gamma, and Heat Shock Cognate 71

Novel insights on proteins involved in Alzheimer's disease (AD) are needed. Since multiple cell types and matrix components are altered in AD, bulk analysis of brain tissue maybe difficult to interpret. In the current study, we isolated pyramidal cells from the cornu ammonis 1 (CA1) region of t...

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Veröffentlicht in:	Frontiers in aging neuroscience 2021-11, Vol.13, p.735334-735334, Article 735334
Hauptverfasser:	Sandebring-Matton, Anna, Axenhus, Michael, Bogdanovic, Nenad, Winblad, Bengt, Schedin-Weiss, Sophia, Nilsson, Per, Tjernberg, Lars O.
Format:	Artikel
Sprache:	eng
Schlagworte:	14-3-3 protein 14-3-3-γ Adenosine triphosphate Aging Alzheimer's disease Brain Cortex (frontal) Creatine Creatine kinase creatine kinase B Geriatrics & Gerontology Heat shock heat shock cognate 71 High-performance liquid chromatography Hippocampus Immunohistochemistry Kinases laser capture microscopy Lasers Life Sciences & Biomedicine Medicin och hälsovetenskap Neurodegenerative diseases Neuropathology Neuroscience Neurosciences Neurosciences & Neurology Polyethylene terephthalate Proteins Proteomes Proteomics Pyramidal cells Science & Technology
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