Autoantibodies and SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies

The relation between infections and autoimmune diseases has been extensively investigated. Multiple studies suggest a causal relation between these two entities with molecular mimicry, hyperstimulation and dysregulation of the immune system as plausible mechanisms. The recent pandemic with a new vir...

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Veröffentlicht in:Autoimmunity reviews 2022-03, Vol.21 (3), p.103012-103012, Article 103012
Hauptverfasser: Damoiseaux, Jan, Dotan, Arad, Fritzler, Marvin J., Bogdanos, Dimitrios P., Meroni, Pier Luigi, Roggenbuck, Dirk, Goldman, Michel, Landegren, Nils, Bastard, Paul, Shoenfeld, Yehuda, Conrad, Karsten
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container_end_page 103012
container_issue 3
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container_title Autoimmunity reviews
container_volume 21
creator Damoiseaux, Jan
Dotan, Arad
Fritzler, Marvin J.
Bogdanos, Dimitrios P.
Meroni, Pier Luigi
Roggenbuck, Dirk
Goldman, Michel
Landegren, Nils
Bastard, Paul
Shoenfeld, Yehuda
Conrad, Karsten
description The relation between infections and autoimmune diseases has been extensively investigated. Multiple studies suggest a causal relation between these two entities with molecular mimicry, hyperstimulation and dysregulation of the immune system as plausible mechanisms. The recent pandemic with a new virus, i.e., SARS-CoV-2, has resulted in numerous studies addressing the potential of this virus to induce autoimmunity and, eventually, autoimmune disease. In addition, it has also revealed that pre-existing auto-immunity (auto-Abs neutralizing type I IFNs) could cause life-threatening disease. Therefore, the topic of the 15th Dresden Symposium on Autoantibodies was focused on autoimmunity in the SARS-CoV-2 era. This report is a collection and distillation of the topics presented at this meeting.
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subjects Anti-IFNa
Anti-IFNα
Antiphospholipid syndrome
Autoantibodies
Autoimmunity
COVID-19
Humans
Medicin och hälsovetenskap
MIS-C
Molecular mimicry
Review
RNA, Viral
SARS-CoV-2
title Autoantibodies and SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies
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