Autoantibodies and SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies
The relation between infections and autoimmune diseases has been extensively investigated. Multiple studies suggest a causal relation between these two entities with molecular mimicry, hyperstimulation and dysregulation of the immune system as plausible mechanisms. The recent pandemic with a new vir...
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Veröffentlicht in: | Autoimmunity reviews 2022-03, Vol.21 (3), p.103012-103012, Article 103012 |
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creator | Damoiseaux, Jan Dotan, Arad Fritzler, Marvin J. Bogdanos, Dimitrios P. Meroni, Pier Luigi Roggenbuck, Dirk Goldman, Michel Landegren, Nils Bastard, Paul Shoenfeld, Yehuda Conrad, Karsten |
description | The relation between infections and autoimmune diseases has been extensively investigated. Multiple studies suggest a causal relation between these two entities with molecular mimicry, hyperstimulation and dysregulation of the immune system as plausible mechanisms. The recent pandemic with a new virus, i.e., SARS-CoV-2, has resulted in numerous studies addressing the potential of this virus to induce autoimmunity and, eventually, autoimmune disease. In addition, it has also revealed that pre-existing auto-immunity (auto-Abs neutralizing type I IFNs) could cause life-threatening disease. Therefore, the topic of the 15th Dresden Symposium on Autoantibodies was focused on autoimmunity in the SARS-CoV-2 era. This report is a collection and distillation of the topics presented at this meeting. |
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subjects | Anti-IFNa Anti-IFNα Antiphospholipid syndrome Autoantibodies Autoimmunity COVID-19 Humans Medicin och hälsovetenskap MIS-C Molecular mimicry Review RNA, Viral SARS-CoV-2 |
title | Autoantibodies and SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies |
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