Growth and CD4 patterns of adolescents living with perinatally acquired HIV worldwide, a CIPHER cohort collaboration analysis

Introduction Adolescents living with HIV are subject to multiple co‐morbidities, including growth retardation and immunodeficiency. We describe growth and CD4 evolution during adolescence using data from the Collaborative Initiative for Paediatric HIV Education and Research (CIPHER) global project....

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Veröffentlicht in:	JOURNAL OF THE INTERNATIONAL AIDS SOCIETY 2022-03, Vol.25 (3), p.e25871-n/a
Hauptverfasser:	Jesson, Julie, Crichton, Siobhan, Quartagno, Matteo, Yotebieng, Marcel, Abrams, Elaine J., Chokephaibulkit, Kulkanya, Le Coeur, Sophie, Aké‐Assi, Marie‐Hélène, Patel, Kunjal, Pinto, Jorge, Paul, Mary, Vreeman, Rachel, Davies, Mary‐Ann, Ben‐Farhat, Jihane, Van Dyke, Russell, Judd, Ali, Mofenson, Lynne, Vicari, Marissa, Seage, George, Bekker, Linda‐Gail, Essajee, Shaffiq, Gibb, Diana, Penazzato, Martina, Collins, Intira Jeannie, Wools‐Kaloustian, Kara, Slogrove, Amy, Powis, Kate, Williams, Paige, Matshaba, Mogomotsi, Thahane, Lineo, Nyasulu, Phoebe, Lukhele, Bhekumusa, Mwita, Lumumba, Kekitiinwa‐Rukyalekere, Adeodata, Wanless, Sebastian, Goetghebuer, Tessa, Thorne, Claire, Warszawski, Josiane, Galli, Luisa, Rossum, Annemarie M.C, Giaquinto, Carlo, Marczynska, Magdalena, Marques, Laura, Prata, Filipa, Ene, Luminita, Okhonskaya, Lyuba, Navarro, Marisa, Frick, Antoinette, Naver, Lars, Kahlert, Christian, Volokha, Alla, Chappell, Elizabeth, Pape, Jean William, Rouzier, Vanessa, Marcelin, Adias, Succi, Regina, Sohn, Annette H., Kariminia, Azar, Edmonds, Andrew, Lelo, Patricia, Lyamuya, Rita, Ogalo, Edith Apondi, Odhiambo, Francesca Akoth, Haas, Andreas D., Bolton, Carolyn, Muhairwe, Josephine, Tweya, Hannock, Sylla, Mariam, D'Almeida, Marceline, Renner, Lorna, Abzug, Mark J., Oleske, James, Purswani, Murli, Teasdale, Chloe, Nuwagaba‐Biribonwoha, Harriet, Goodall, Ruth, Leroy, Valériane
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adolescent Adolescent development Adolescents Adult AIDS Antiretroviral agents CD4 CD4 Lymphocyte Count CD4 lymphocytes Child Child, Preschool Cohort analysis Cohort Studies Collaboration Complications and side effects Female Growth Growth Disorders - epidemiology Health aspects HIV HIV infection HIV Infections - drug therapy HIV Infections - epidemiology Human immunodeficiency virus Humans Income International aspects Life Sciences Male Pediatric research Perinatal infection perinatally acquired Sexually transmitted diseases Statistics STD Teenagers
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Zusammenfassung:	Introduction Adolescents living with HIV are subject to multiple co‐morbidities, including growth retardation and immunodeficiency. We describe growth and CD4 evolution during adolescence using data from the Collaborative Initiative for Paediatric HIV Education and Research (CIPHER) global project. Methods Data were collected between 1994 and 2015 from 11 CIPHER networks worldwide. Adolescents with perinatally acquired HIV infection (APH) who initiated antiretroviral therapy (ART) before age 10 years, with at least one height or CD4 count measurement while aged 10–17 years, were included. Growth was measured using height‐for‐age Z‐scores (HAZ, stunting if
ISSN:	1758-2652 1758-2652
DOI:	10.1002/jia2.25871