Genetically Predicted Circulating Copper and Risk of Chronic Kidney Disease: A Mendelian Randomization Study

Elevated circulating copper levels have been associated with chronic kidney disease (CKD), kidney damage, and decline in kidney function. Using a two sample Mendelian randomization approach where copper-associated genetic variants were used as instrumental variables, genetically predicted higher cir...

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Veröffentlicht in:	NUTRIENTS 2022-01, Vol.14 (3), p.509
Hauptverfasser:	Ahmad, Shafqat, Ärnlöv, Johan, Larsson, Susanna C
Format:	Artikel
Sprache:	eng
Schlagworte:	Biobanks Circulating nutrients circulating nutrients. kidney related disease Communication Confidence intervals Consortia Copper Creatinine Epidemiology Estimated glomerular filtration rate Estimates Genetic diversity Genetic Predisposition to Disease Genetic variance Genomes Glomerular filtration rate Glomerular Filtration Rate - genetics Health risks Humans Hypotheses Kidney diseases Kidney related disease Kidneys Mendelian randomization Mendelian Randomization Analysis Meta-analysis Methods Oxidative stress Randomization Renal Insufficiency, Chronic - epidemiology Renal Insufficiency, Chronic - genetics Risk analysis Risk factors
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