Gut microbiota–derived metabolite trimethylamine-N-oxide and multiple health outcomes: an umbrella review and updated meta-analysis

Trimethylamine-N-oxide (TMAO) is a gut microbiota–derived metabolite produced from dietary nutrients. Many studies have discovered that circulating TMAO concentrations are linked to a wide range of health outcomes. This study aimed to summarize health outcomes related to circulating TMAO concentrati...

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Veröffentlicht in:	The American journal of clinical nutrition 2022-07, Vol.116 (1), p.230-243
Hauptverfasser:	Li, Doudou, Lu, Ying, Yuan, Shuai, Cai, Xiaxia, He, Yuan, Chen, Jie, Wu, Qiong, He, Di, Fang, Aiping, Bo, Yacong, Song, Peige, Bogaert, Debby, Tsilidis, Kostas, Larsson, Susanna C, Yu, Huanling, Zhu, Huilian, Theodoratou, Evropi, Zhu, Yimin, Li, Xue
Format:	Artikel
Sprache:	eng
Schlagworte:	all-cause mortality Biomarkers Cancer cardiovascular disease Cardiovascular diseases Cardiovascular Diseases - etiology Diabetes Mellitus Diet Gastrointestinal Microbiome Glomerular filtration rate Heterogeneity Humans Hypertension Hypertension - complications Intestinal microflora Meta-analysis Metabolites Methylamines - metabolism Microbiota Mortality Neoplasms - complications Nutrients Original Research Communications Oxides Renal function Reviews Risk Factors TMAO Trimethylamine Trimethylamine-N-oxide umbrella review updated meta-analyses
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