Bone mineral density and risk of breast cancer: A cohort study and Mendelian randomization analysis

BACKGROUND Estrogen is involved in both bone metabolism and breast cancer proliferation. However, evidence about the risk of breast cancer according to women's bone mineral density (BMD) is scarce, and little is known about their causal associations. METHODS Women participating in the UK Bioban...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer 2022-07, Vol.128 (14), p.2768-2776
Hauptverfasser:	Zhang, Yanyu, Mao, Xinhe, Yu, Xingxing, Huang, Xiaoxi, He, Wei, Yang, Haomin
Format:	Artikel
Sprache:	eng
Schlagworte:	Alpha-Ketoglutarate-Dependent Dioxygenase FTO - genetics Biobanks Biomedical materials Bone cancer Bone density Bone Density - genetics Bone mineral density Bone turnover Breast cancer Breast Neoplasms - epidemiology Breast Neoplasms - genetics Cohort analysis Cohort Studies Estrogen receptors Estrogens Female Genetic diversity Genetic variance Genome-Wide Association Study Genomes Health risks Humans Medicin och hälsovetenskap Mendelian randomization Mendelian Randomization Analysis Metabolism Oncology Osteoporosis Pleiotropy Polymorphism, Single Nucleotide Post-menopause Randomization Regression analysis Regression models Risk
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!